Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for August 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
FDA Could Green-Light COVID-19 Vaccines Before Clinical Trials Completed
MONDAY, Aug. 31, 2020 (HealthDay News) — Emergency use authorization (EUA) or approval for a COVID-19 vaccine before phase 3 clinical trials are complete could be considered by the U.S. Food and Drug Administration, according to the agency’s commissioner, Stephen Hahn, M.D.
Follow-up Calls After Mohs Surgery Do Not Boost Satisfaction
MONDAY, Aug. 31, 2020 (HealthDay News) — Postoperative follow-up telephone calls (TFU) to patients after Mohs micrographic surgery (MMS) do not improve patient satisfaction, according to a research letter published online July 31 in the Journal of the American Academy of Dermatology.
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Long-Term Follow-Up Reported for BP Telemonitoring Program
MONDAY, Aug. 31, 2020 (HealthDay News) — Among adults with uncontrolled blood pressure, fewer cardiovascular events and lower costs were observed at five years with a pharmacist-led telemonitoring program, but the differences were not statistically significant compared with usual care, according to a study published online Aug. 31 in Hypertension.
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Use of Performance-Enhancing Substances Tied to Risk Behaviors
MONDAY, Aug. 31, 2020 (HealthDay News) — Use of legal performance-enhancing substances (PES) in young adults is associated with an increased likelihood of future problematic alcohol use and drinking-related risk behaviors, according to a study published online Aug. 31 in Pediatrics.
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Vitamin C Positively Linked to Skeletal Muscle Mass Measures
FRIDAY, Aug. 28, 2020 (HealthDay News) — Dietary and circulating vitamin C are positively associated with measures of skeletal muscle mass in middle- and older-aged men and women, according to a study published online Aug. 27 in The Journal of Nutrition.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 24 to 28, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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FDA Warns of Hand Sanitizers in Food-Like Packaging
FRIDAY, Aug. 28, 2020 (HealthDay News) — A warning about alcohol-based hand sanitizers in packaging that looks like food or drink has been issued by the U.S. Food and Drug Administration.
Model Says COVID-19 Deaths Could Surpass 317,000 by December
FRIDAY, Aug. 28, 2020 (HealthDay News) — A widely cited model for COVID-19 deaths in the United States predicts a total of 317,000 deaths by December.
Early Use of Empiric Antibacterial Therapy Common in COVID-19
FRIDAY, Aug. 28, 2020 (HealthDay News) — Early empiric antibacterial therapy use is high in patients hospitalized with COVID-19, according to a study published online Aug. 21 in Clinical Infectious Diseases.
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Mortality, Intubation Rates Lower With Anticoagulation in COVID-19
FRIDAY, Aug. 28, 2020 (HealthDay News) — Among hospitalized patients with COVID-19, anticoagulation (AC) is associated with reduced mortality and intubation, according to a study published online Aug. 26 in the Journal of the American College of Cardiology.
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Parents Have Contradictory Views on Childhood Vaccines
THURSDAY, Aug. 27, 2020 (HealthDay News) — The vast majority of parents believe vaccines are the best way to protect their children from infectious diseases, yet two-thirds are still nervous to take their children to their pediatrician’s office during the COVID-19 pandemic, according to the results of a survey released by Orlando Health.
Program Improves Use of Chronic Opioid Therapy in HIV Care
THURSDAY, Aug. 27, 2020 (HealthDay News) — The TEACH (Targeting Effective Analgesia in Clinics for HIV) intervention is a promising strategy for improving adherence to opioid prescribing guidelines among HIV care providers and their patients on chronic opioid therapy (COT), according to a study published online July 22 in Clinical Infectious Diseases.
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Recovery Protocol Cuts Opioid Use After Elective Neurosurgery
THURSDAY, Aug. 27, 2020 (HealthDay News) — Enhanced recovery after surgery (ERAS) protocols can reduce postoperative use of opioids in patients undergoing elective spine and peripheral nerve surgical procedures, according to a study published online Aug. 6 in Pain Medicine.
Topical Calcineurin Inhibitors Not Tied to Skin Cancer
THURSDAY, Aug. 27, 2020 (HealthDay News) — There is no association between use of topical calcineurin inhibitors (TCIs) for the treatment of atopic dermatitis (AD) and an increased risk for skin cancer, according to a study published online Aug. 12 in JAMA Dermatology.
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About Half of Waivered Clinicians Prescribe Buprenorphine for OUD
WEDNESDAY, Aug. 26, 2020 (HealthDay News) — About half of waivered clinicians prescribe buprenorphine for opioid use disorder and most treat at levels below their patient limits, according to a research letter published online Aug. 24 in JAMA Network Open.
About One in Three Multiple Sclerosis Patients Have Migraine
WEDNESDAY, Aug. 26, 2020 (HealthDay News) — Internationally, more than three in 10 patients with multiple sclerosis (MS) have migraine, according to a review published in the September issue of the Journal of Clinical Neuroscience.
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Escitalopram Reduces Symptoms of Anxiety in Teens With GAD
WEDNESDAY, Aug. 26, 2020 (HealthDay News) — For adolescents with generalized anxiety disorder (GAD), escitalopram reduces symptoms of anxiety, according to a study published online Aug. 25 in The Journal of Clinical Psychiatry.
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Vitamin D Supplement No Benefit in Pediatric Persistent Asthma
TUESDAY, Aug. 25, 2020 (HealthDay News) — Vitamin D3 supplementation does not prolong the time to severe asthma exacerbation among children with persistent asthma and low vitamin D levels, according to a study published in the Aug. 25 issue of the Journal of the American Medical Association.
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Clinical Impact of Remdesivir in Moderate COVID-19 Unclear
MONDAY, Aug. 24, 2020 (HealthDay News) — Patients with moderate COVID-19 receiving a five-day course of remdesivir have a statistically significant difference in clinical status compared with usual care, according to a study published online Aug. 21 in the Journal of the American Medical Association.
School-Located Influenza Vaccine Intervention Beneficial
MONDAY, Aug. 24, 2020 (HealthDay News) — A school-located influenza vaccination (SLIV) intervention is associated with a reduction in the incidence of influenza hospitalization, according to a study published online Aug. 18 in PLOS Medicine.
Antihypertensive Agents Not Tied to Higher Risk for Depression
MONDAY, Aug. 24, 2020 (HealthDay News) — Nine individual antihypertensive agents from the classes of angiotensin agents, calcium antagonists, and β-blockers are associated with reduced rates of depression, according to a study published online Aug. 24 in Hypertension.
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RAAS Inhibitors May Benefit HTN Patients With COVID-19
MONDAY, Aug. 24, 2020 (HealthDay News) — Renin-angiotensin-aldosterone system (RAAS) inhibitors are beneficial for hypertensive patients with COVID-19, according to a study published online Aug. 24 in Current Atherosclerosis Reports.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 17 to 21, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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White House Blocks FDA’s Power to Regulate Lab Tests
FRIDAY, Aug. 21, 2020 (HealthDay News) — The Trump administration has blocked the U.S. Food and Drug Administration from regulating a wide swath of laboratory tests, including ones for COVID-19.
Extract From Deadly Plant Touted as COVID-19 Cure
FRIDAY, Aug. 21, 2020 (HealthDay News) — Experts have slammed claims by a major Trump donor that an extract from a deadly plant is a cure for COVID-19.
ACIP Issues Recommendations for 2020 to 2021 Flu Vaccination
FRIDAY, Aug. 21, 2020 (HealthDay News) — Advisory Committee on Immunization Practices (ACIP) recommendations have been updated to include the influenza vaccination for the 2020 to 2021 season; the recommendations were published in the Aug. 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
Adolescent Vaccinations Decreased During COVID-19 Pandemic
FRIDAY, Aug. 21, 2020 (HealthDay News) — The decrease in vaccination orders seen during the COVID-19 pandemic could offset increases in vaccinations for adolescents from 2018 to 2019, according to research published in the Aug. 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
Nonopioid Pain Protocol Feasible After Sports Orthopedic Surgery
FRIDAY, Aug. 21, 2020 (HealthDay News) — For patients undergoing common orthopedic sports procedures, a multimodal, nonopioid pain protocol featuring little or no use of opioids is feasible for managing postoperative pain, according to a study published in the August issue of Arthroscopy.
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Short-Term PrEP Feasible for Men at Risk for HIV on Vacation
THURSDAY, Aug. 20, 2020 (HealthDay News) — Preexposure prophylaxis (PrEP) is well tolerated by men who have sex with men (MSM) at episodic risk for HIV while on vacation, according to a study published online Aug. 15 in the Journal of Acquired Immune Deficiency Syndrome.
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Longer Bisphosphonate Use May Up Atypical Femur Fracture Risk
THURSDAY, Aug. 20, 2020 (HealthDay News) — Longer duration of bisphosphonate use is associated with an increased risk for atypical femur fracture, according to a study published in the Aug. 20 issue of the New England Journal of Medicine.
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Evinacumab Cuts LDL-C Level in Familial Hypercholesterolemia
THURSDAY, Aug. 20, 2020 (HealthDay News) — For patients with homozygous familial hypercholesterolemia, evinacumab lowers low-density lipoprotein (LDL) cholesterol levels, according to a study published in the Aug. 20 issue of the New England Journal of Medicine.
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Antibiotic Exposure Linked to Risk for Inflammatory Bowel Disease
THURSDAY, Aug. 20, 2020 (HealthDay News) — Higher cumulative exposure to antibiotics is associated with an increased risk for new-onset inflammatory bowel disease (IBD), according to a study published online Aug. 17 in The Lancet Gastroenterology & Hepatology.
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HHS: Pharmacists in All States Can Give Childhood Vaccinations
WEDNESDAY, Aug. 19, 2020 (HealthDay News) — Children can now be vaccinated by pharmacists in all 50 states as the U.S. government seeks to prevent a decline in routine vaccinations during the COVID-19 pandemic.
Honey Beats Usual Care for Upper Respiratory Tract Infections
WEDNESDAY, Aug. 19, 2020 (HealthDay News) — For upper respiratory tract infections (URTIs), honey seems superior to usual care, according to a review and meta-analysis published online Aug. 18 in BMJ Evidence-Based Medicine.
CNS-Active Meds Often Prescribed for Older Adults With Dementia
WEDNESDAY, Aug. 19, 2020 (HealthDay News) — Patients with dementia are frequently prescribed central nervous system (CNS)-active medications, according to a research letter published online Aug. 18 in the Journal of the American Medical Association.
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Antibiotics May Reduce Efficacy of Hormonal Contraceptives
WEDNESDAY, Aug. 19, 2020 (HealthDay News) — The efficacy of hormonal contraceptives may be reduced with use of antibiotics, according to a study published online Aug. 18 in BMJ Evidence-Based Medicine.
Combination Therapy May Benefit Some With Kawasaki Disease
WEDNESDAY, Aug. 19, 2020 (HealthDay News) — Adding corticosteroids to initial intravenous immunoglobulin seems beneficial for preventing coronary artery abnormalities in high-risk patients with Kawasaki disease (KD), according to a study published online Aug. 19 in the Journal of the American Heart Association.
Bariatric Surgery Linked to Reduction in Mortality Rate
TUESDAY, Aug. 18, 2020 (HealthDay News) — Bariatric surgery is associated with a reduction in mortality, and Roux-en-Y gastric bypass (RYGB) is effective for blood pressure (BP) control in patients with hypertension and obesity, according to two studies published online Aug. 18 in the Annals of Internal Medicine.
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Homicide, Suicide, and Overdose Leading Causes of Maternal Death 
Model Predicts Poor Outcomes Within 30 Days of a Before Medically Advised Discharge 
Fewer Than Half of Drug Overdose Survivors Go to the Hospital 
2000 to 2023 Saw Rise in Pediatric Exposure to Medications, Supplements 
Holding DMARDs at Time of COVID-19 Vaccine Not Warranted in Those With Inflammatory Arthritis 
1 in 3 With Lupus Take Supplements, Medications With Potential for Interactions 
2013 to 2024 Saw Decrease in Benzodiazepine Prescribing 
GLP-1 Receptor Agonists, SGLT-2is Slow Renal Function Decline in T2D With Albuminuria 
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