Endolymphatic Sac Decompression Effective for Vertigo, Migraine

WEDNESDAY, May 28, 2025 (HealthDay News) — For Meniere disease (MD) patients with migraine, endolymphatic sac decompression (ELSD) is effective, providing postoperative relief of vertigo and migraine, according to a study published online April 30 in Acta Oto-Laryngologica.

Lin Han, from Peking University in Beijing, and colleagues enrolled 104 MD patients to examine the relation of MD and migraine. To assess effectiveness at pre- and post-ELSD, monthly vertigo episodes and the migraine headache index were used. Vertigo relief rates were compared for patients divided into MD with migraine and MD alone; postoperative relief of vertigo and migraine was then assessed in MD patients with migraine.

The researchers found that the postoperative vertigo relief rates were 46.7 and 40.68 percent for MD alone and MD with migraine, respectively, with no significant difference noted. Postoperative monthly vertigo episodes and the migraine headache index decreased significantly in MD patients with migraine. The kappa value was 0.505 for vertigo and migraine outcomes. Independent predictive relief of vertigo and migraine was seen with the absence of hypertension. Male gender was independently predictive for migraine relief.

“The postoperative relief of vertigo and migraine has a certain consistency, suggesting that these two diseases may share some common pathogenesis related to inflammation,” the authors write.

Abstract/Full Text