Here are what the editors at HealthDay consider to be the most important developments in Neurology for January 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
AHA: Nearly Half of U.S. Adults Have Cardiovascular Disease
THURSDAY, Jan. 31, 2019 (HealthDay News) — The prevalence of cardiovascular disease (CVD) is 48.0 percent in adults in the United States based on 2013 to 2016 data, according to a report published online Jan. 31 in Circulation.
Management of MS in Pregnancy Reviewed in U.K. Guideline
THURSDAY, Jan. 31, 2019 (HealthDay News) — It is important to discuss family planning and pregnancy proactively in women of childbearing age who have multiple sclerosis (MS), according to a review published online Jan. 5 in Practical Neurology.
Aerobic Exercise Tied to Better Cognition at All Ages
WEDNESDAY, Jan. 30, 2019 (HealthDay News) — Aerobic exercise contributes to brain health in individuals as young as 20 years, according to a study published online Jan. 30 in Neurology.
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Thymectomy + PDN Beneficial for Non-Thymomatous Myasthenia Gravis
WEDNESDAY, Jan. 30, 2019 (HealthDay News) — For patients with non-thymomatous myasthenia gravis, thymectomy plus prednisone confers benefits versus prednisone alone at five years, according to a study published online Jan. 25 in The Lancet Neurology.
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Intensive BP Treatment Does Not Reduce Dementia Risk
TUESDAY, Jan. 29, 2019 (HealthDay News) — Treating systolic blood pressure (BP) to a goal of less than 120 mm Hg rather than 140 mm Hg does not result in a significant reduction in the risk for probable dementia, according to a study published online Jan. 28 in the Journal of the American Medical Association.
NOACs Recommended as First-Line Prevention of Stroke in A-Fib
TUESDAY, Jan. 29, 2019 (HealthDay News) — For patients with atrial fibrillation, novel oral anticoagulants (NOACs) are recommended over warfarin to prevent stroke and weight loss is recommended for overweight and obese individuals, according to updated guidelines published online Jan. 28 in Circulation.
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Screen Time Linked to Poorer Child Developmental Performance
MONDAY, Jan. 28, 2019 (HealthDay News) — Screen time is associated with poorer performance on developmental screening tests among young children, according to a study published online Jan. 28 in JAMA Pediatrics.
Helmet Use Low Among Standing Electric Scooter Riders
MONDAY, Jan. 28, 2019 (HealthDay News) — Helmet use is low among patients presenting to the emergency department with injuries associated with standing electric scooter use, according to a study published online Jan. 25 in JAMA Network Open.
Machine Learning Methods Can Detect UTI in Dementia Patients
MONDAY, Jan. 28, 2019 (HealthDay News) — Algorithms that combine Internet of Things (IoT) technologies and in-home sensory devices with machine learning techniques can be used to monitor the health and well-being of people with dementia, according to a study published online Jan. 15 in PLOS ONE.
Comorbid Neck Injury Up for Women With Concussion
MONDAY, Jan. 28, 2019 (HealthDay News) — Female patients with a concussion-related emergency department visit have an increased risk for comorbid neck injury, according to a study published online Dec. 28 in the Journal of Women’s Health.
Virtual Video Visits Liked by Patients, Providers
FRIDAY, Jan. 25, 2019 (HealthDay News) — Virtual video visits can effectively replace office visits for selected patients across medical specialties without sacrificing quality of care or patient-physician communication, according to a study published in the January issue of the American Journal of Managed Care.
Suicide Incidence Up in Autism Spectrum Disorder 2013 to 2017
FRIDAY, Jan. 25, 2019 (HealthDay News) — Between 2013 and 2017, the cumulative incidence of suicide was higher in the autism spectrum disorder (ASD) population compared with the non-ASD population, according to a study published online Jan. 21 in Autism Research.
Cognitive Scores After Kidney Transplant Tied to Frailty
FRIDAY, Jan. 25, 2019 (HealthDay News) — Frail kidney transplant recipients have lower cognitive scores than nonfrail recipients four years after transplant, according to a study published online Jan. 24 in the Journal of the American Society of Nephrology.
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Report IDs Areas Lacking Good Practice in Health Tech Assessment
FRIDAY, Jan. 25, 2019 (HealthDay News) — In a report published in the January issue of Value in Health, an ISPOR–The Professional Society for Health Economics and Outcomes Research working group indicates the lack of good practices in three areas of health technology assessment (HTA).
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Risk for Conversion of MS Varies With Different Therapies
WEDNESDAY, Jan. 16, 2019 (HealthDay News) — For relapsing-remitting multiple sclerosis (MS), the risk for conversion to secondary progressive MS is lower with initial treatment with fingolimod, alemtuzumab, or natalizumab versus glatiramer acetate or interferon beta, according to a study published online in the Jan. 15 issue of the Journal of the American Medical Association.
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Levodopa + Carbidopa Does Not Modify Disease in Early Parkinson
THURSDAY, Jan. 24, 2019 (HealthDay News) — For patients with early Parkinson disease, treatment with levodopa combined with carbidopa has no disease-modifying effect, according to a study published in the Jan. 24 issue of the New England Journal of Medicine.
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BP >120/80 mm Hg Linked to Lower Gray Matter Volume
THURSDAY, Jan. 24, 2019 (HealthDay News) — In young adults, lower gray matter volume (GMV) is seen in individuals with blood pressure (BP) >120/80 mm Hg, according to a study published online Jan. 23 in Neurology.
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Most Stroke Survivors ≥50 Years Report Complete Mental Health
WEDNESDAY, Jan. 23, 2019 (HealthDay News) — More than two-thirds of stroke survivors aged 50 years or older report being in complete mental health (CMH), according to a study published online Jan. 9 in the Journal of Aging and Health.
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Mavoglurant Improves Visual Attention in Fragile X Syndrome
WEDNESDAY, Jan. 23, 2019 (HealthDay News) — For patients with fragile X syndrome (FXS), mavoglurant treatment improves visual attention and pupil reactivity, according to a study published online Jan. 17 in PLOS ONE.
Canadian Syncope Risk Score IDs ED Monitoring Time Postsyncope
TUESDAY, Jan. 22, 2019 (HealthDay News) — The risk for arrhythmic conditions can be identified quickly among patients with syncope presenting to the emergency department, according to a study published online Jan. 21 in Circulation.
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Medical Cannabis Decisions Being Made by Users, Not Doctors
TUESDAY, Jan. 22, 2019 (HealthDay News) — Many patients use medical cannabis without their mainstream health care provider’s knowledge, and further, they self-adjust their pharmaceutical use in response to cannabis use, according to a study published online Jan. 8 in the Journal of Psychoactive Drugs.
Frailty Could Increase Susceptibility for Dementia
FRIDAY, Jan. 18, 2019 (HealthDay News) — Frailty and Alzheimer disease-related brain changes independently contribute to dementia status, according to a study published in the February issue of The Lancet Neurology.
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FDA Down to 5 Weeks of Funding to Review New Drug Applications
THURSDAY, Jan. 17, 2019 (HealthDay News) — Due to the federal government shutdown, the U.S. Food and Drug Administration has only about five weeks of funding left to review new drug applications, according to Commissioner Scott Gottlieb, M.D.
FDA Approves First Generic Version of Epilepsy Drug Sabril
THURSDAY, Jan. 17, 2019 (HealthDay News) — The first generic version of Sabril (vigabatrin) has been approved by the U.S. Food and Drug Administration to prevent complex partial seizures in adults and children aged 10 years and older with epilepsy.
Nerve Transfer Promising for Acute Flaccid Myelitis Patients
THURSDAY, Jan. 17, 2019 (HealthDay News) — Two patients diagnosed with acute flaccid myelitis and upper-extremity neuropathy who were treated with peripheral nerve transfer continue to demonstrate functional recovery at two years, according to a case series recently published in Pediatric Neurology.
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Temporary Impairment in HRQOL After Teen Sports Concussion
THURSDAY, Jan. 17, 2019 (HealthDay News) — Adolescent sports-related concussion (SRC) is associated with temporary impairments in health-related quality of life (HRQOL), according to a study published online Jan. 15 in the Journal of Neurosurgery: Pediatrics.
Adoption of Advanced Health IT Capabilities Inconsistent
WEDNESDAY, Jan. 16, 2019 (HealthDay News) — Adoption of advanced health information technology (HIT) capabilities is inconsistent across health care systems, with electronic health record (EHR) standardization being the strongest predictor of advanced capabilities, according to a study published in the January issue of the American Journal of Managed Care.
High Levels of Activity, Motor Ability Linked to Better Cognition
WEDNESDAY, Jan. 16, 2019 (HealthDay News) — In older adults, higher levels of total daily activity and better motor abilities are associated with better cognition, according to a study published online Jan. 16 in Neurology.
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Breakdown of Blood-Brain Barrier May Drive Dementia
TUESDAY, Jan. 15, 2019 (HealthDay News) — Breakdown of the blood-brain barrier (BBB) may be an early biomarker of cognitive dysfunction, independent of amyloid or tau marker status, according to a study published online Jan. 14 in Nature Medicine.
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Stem Cell Transplant Slows Progression of Multiple Sclerosis
TUESDAY, Jan. 15, 2019 (HealthDay News) — For patients with relapsing-remitting multiple sclerosis (MS), nonmyeloablative hematopoietic stem cell transplantation (HCST) is associated with prolonged time to disease progression compared with disease-modifying therapy (DMT), according to a study published in the Jan. 15 issue of the Journal of the American Medical Association.
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Study Explores Influence of Genetics, Environment in Disease
TUESDAY, Jan. 15, 2019 (HealthDay News) — The influence of heritability and environmental factors has been identified for a large number of phenotypes, according to a study published online Jan. 14 in Nature Genetics.
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Cardiometabolic Risk Up With Tourette, Chronic Tic Disorder
TUESDAY, Jan. 15, 2019 (HealthDay News) — Patients with Tourette syndrome (TS) or chronic tic disorder (CTD) have an increased risk for developing at least one metabolic or cardiovascular disorder, according to a study published online Jan. 14 in JAMA Neurology.
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American College of Physicians Releases 7th Edition of Ethics Manual
TUESDAY, Jan. 15, 2019 (HealthDay News) — Ethical principles are discussed in an updated Ethics Manual, issued by the American College of Physicians (ACP) and published as a supplement to the Jan. 15 issue of the Annals of Internal Medicine.
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Terrorist Attack Victims With PTSD Have Higher Cancer Risk
MONDAY, Jan. 14, 2019 (HealthDay News) — Among individuals with posttraumatic stress disorder (PTSD), those who were victims of terrorist attacks (TA) have a higher risk for neoplasms than those who experience other traumatic events (OTE), according to a study published online Jan. 8 in the Journal of Neuroscience Research.
One in Five Back Pain Patients Experience Persistent Pain
MONDAY, Jan. 14, 2019 (HealthDay News) — Eighteen percent of patients with back pain experience a persistent trajectory, according to a study published online Jan. 14 in Arthritis Care & Research.
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Prices Still Explain High U.S. Health Care Spending
FRIDAY, Jan. 11, 2019 (HealthDay News) — The difference in health spending between the United States and other countries is still explained by health care prices, according to a study published in the January issue of Health Affairs.
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Private Equity Acquisition of Physician Practices Discussed
THURSDAY, Jan. 10, 2019 (HealthDay News) — The phenomenon of private equity acquisition of physician practices is discussed in an Ideas and Opinions piece published online Jan. 8 in the Annals of Internal Medicine.
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Less Deep Sleep in Elderly Tied to Alzheimer Disease Markers
THURSDAY, Jan. 10, 2019 (HealthDay News) — Older people who have less slow wave sleep have higher levels of the brain protein tau, a marker of brain damage and Alzheimer disease (AD), according to a study published in the Jan. 9 issue of Science Translational Medicine.
Obesity Linked to Lower Gray Matter Brain Volume
WEDNESDAY, Jan. 9, 2019 (HealthDay News) — Obesity is associated with lower gray matter brain volumes, according to a study published online Jan. 9 in Neurology.
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Psychotherapy May Reduce Frequency of Nonepileptic Seizures
WEDNESDAY, Jan. 9, 2019 (HealthDay News) — Adherence to psychotherapy is associated with improved outcomes in individuals with psychogenic nonepileptic seizures (PNES), according to a study published online Jan. 4 in Neurology.
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Low Levels of Placental Growth Factor in Pregnancy Linked to Subsequent ADHD in Offspring .jpg)
Time-Restricted Eating Shows Possible Benefits for Patients With Huntington Disease 
Past Blast Exposure Tied to Long-Term Chronic Medical Diagnoses in Veterans 
Women With Cerebral Palsy Receive Less Preventive Gynecological Care 
People With ADHD Experience 50 Percent More GI Symptoms 
1 in 4 Former NFL Players Had CTE at Death in 2016 to 2021 
Many With Atypical Alzheimer Disease Do Not Qualify for Anti-Amyloid Therapy 
Frequent TV Watching Linked to Smaller Brain Volume 
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