Here are what the editors at HealthDay consider to be the most important developments in Critical Care for July 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 27 to 31, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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U.S. Puts Up Another $2.1 Billion for Potential COVID-19 Vaccine
FRIDAY, July 31, 2020 (HealthDay News) — The United States is buying up another potential COVID-19 vaccine, the Associated Press reported Friday.
Telemedicine Use Explodes During COVID-19 Pandemic
FRIDAY, July 31, 2020 (HealthDay News) — The emergence of telemedicine has accelerated during the coronavirus pandemic. HD Live! sat down with Rujuta Saksena, M.D., an oncologist at Overlook Medical Center in Summit, New Jersey, and Ateev Mehrotra, M.D., associate professor of health care policy at Harvard Medical School in Boston, to discuss the future of telemedicine and its impact on health care.
Plenty of COVID-19 Vaccine Coming, Fauci Says
FRIDAY, July 31, 2020 (HealthDay News) — When a COVID-19 vaccine is approved, there should be plenty of it available, Anthony Fauci, M.D., infectious diseases chief at the U.S. National Institutes of Health, told a House panel Friday, the Associated Press reported.
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Johns Hopkins University
Bacterial, Fungal Coinfection Uncommon in COVID-19 Patients
FRIDAY, July 31, 2020 (HealthDay News) — Bacterial and fungal infections are uncommon in hospitalized COVID-19 patients, but coinfection is associated with high mortality and antibiotic use is widespread, according to a study published in the July issue of Infection Control & Hospital Epidemiology.
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Global Epidemiology of COVID-19 Reported for Prepandemic Era
FRIDAY, July 31, 2020 (HealthDay News) — Many of the first COVID-19 cases reported from affected countries outside of mainland China involved recent travel to affected countries, according to a study published online July 29 in The Lancet Infectious Diseases.
Sex Differences in Income Vary With Proportion of Male Doctors
FRIDAY, July 31, 2020 (HealthDay News) — For surgical and nonsurgical specialists, sex differences in income vary with the proportion of male physicians in a practice, according to a study published online July 30 in The BMJ.
School Closures Linked to Decreased COVID-19 Incidence, Death
THURSDAY, July 30, 2020 (HealthDay News) — School closures in the United States were temporally associated with decreased COVID-19 incidence and mortality, according to a study published online July 29 in the Journal of the American Medical Association.
Remdesivir Shortages Plague Some Hospitals, Pharmacists Say
THURSDAY, July 30, 2020 (HealthDay News) — One-third of pharmacists say they do not have enough remdesivir to treat all COVID-19 patients who are eligible for it, according to the results of a survey released by the American Society of Health-System Pharmacists (ASHP).
Nirsevimab Injection Cuts RSV-Linked Infections in Preemies
THURSDAY, July 30, 2020 (HealthDay News) — Nirsevimab prevents respiratory syncytial virus (RSV)-associated lower respiratory tract infections in healthy preterm infants, while maternal RSV fusion (F) protein nanoparticle vaccination did not meet the prespecified criterion for efficacy, according to two studies published in the July 30 issue of the New England Journal of Medicine.
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Most Gynecologic Cancer Therapy Not Tied to Higher COVID-19 Risk
THURSDAY, July 30, 2020 (HealthDay News) — For gynecologic oncology patients with COVID-19, the case fatality rate is 14.0 percent, and chemotherapy and recent major surgery do not predict COVID-19 severity or mortality, according to a study published online July 30 in Cancer.
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Latino Communities at Higher Risk for COVID-19
WEDNESDAY, July 29, 2020 (HealthDay News) — Factors linked to structural racism and social determinants of health are associated with an increased risk for COVID-19 in Latino communities, according to a study published online July 23 in the Annals of Epidemiology.
Depression, Anxiety May Be Signs That COVID-19 Is Attacking Brain
WEDNESDAY, July 29, 2020 (HealthDay News) — Depression and anxiety exhibited in COVID-19 patients may be a sign that the virus impacts the central nervous system, as these symptoms are closely associated with a loss of smell and taste rather than more severe manifestations of the virus, according to a study published online July 2 in The Laryngoscope.
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Increase Found in Suicide-Related Exposure Rates to OTC Analgesics
TUESDAY, July 28, 2020 (HealthDay News) — There has been a recent increase in suicide-related exposure rates to over-the-counter (OTC) analgesics, according to a study published online July 26 in Pharmacoepidemiology & Drug Safety.
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Myocardial Injury Seen in Many Early in Recovery From COVID-19
TUESDAY, July 28, 2020 (HealthDay News) — Many patients recently recovered from COVID-19 infection have cardiac involvement, according to a study published online July 27 in JAMA Cardiology.
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FDA Warns Again About Dangers of Methanol-Based Hand Sanitizers
TUESDAY, July 28, 2020 (HealthDay News) — The U.S. Food and Drug Administration is warning consumers not to use alcohol-based hand sanitizers containing methanol, or wood alcohol, which is used in fuel and antifreeze and is toxic if absorbed through the skin or life-threatening if ingested.
COVID-19 Vaccine Candidate Now in Final Phase Testing
MONDAY, July 27, 2020 (HealthDay News) — A vaccine developed by the U.S. National Institutes of Health and Moderna has entered the final phase of testing, the Associated Press reported Monday.
CDC to Address Inequalities in COVID-19 Reporting
MONDAY, July 27, 2020 (HealthDay News) — The U.S. Centers for Disease Control and Prevention plans to take steps to improve how it collects COVID-19 data for blacks, Hispanics, and Native Americans, the Associated Press reports.
Large Proportion of COVID-19 Studies Have Low-Level Evidence
MONDAY, July 27, 2020 (HealthDay News) — A large proportion of studies on COVID-19 have a low level of evidence, according to a research letter published online July 27 in JAMA Internal Medicine.
Impact on Glucocorticoids in COVID-19 Varies With CRP Levels
MONDAY, July 27, 2020 (HealthDay News) — The impact of glucocorticoid treatment on patients with COVID-19 varies according to C-reactive protein (CRP) levels, according to a study published online July 22 in the Journal of Hospital Medicine.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 20 to 24, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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CDC Guidance Issued for Testing, Management of HCP Exposed to Hep C
FRIDAY, July 24, 2020 (HealthDay News) — In a U.S. Centers for Disease Control and Prevention guidance report, published in the July 24 issue of Morbidity and Mortality Weekly Report, recommendations are presented for testing and clinical management of health care personnel (HCP) exposed to the hepatitis C virus (HCV).
Chimpanzee Adenovirus-Vectored Vaccine Promising for COVID-19
FRIDAY, July 24, 2020 (HealthDay News) — A chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein has acceptable safety and induces antibody and T-cell immune responses, according to a study published online July 20 in The Lancet.
Financial Health of Hospitals ‘Dire’ Due to COVID-19
THURSDAY, July 23, 2020 (HealthDay News) — COVID-19 continues to cause financial peril for U.S. hospitals, according to a report released by the American Hospital Association (AHA).
High Prevalence of Americans Have Conditions Linked to Severe COVID-19
THURSDAY, July 23, 2020 (HealthDay News) — The median prevalence of any underlying medical condition that increases the risk for severe COVID-19-associated illness is 47.2 percent among residents in all 50 states and the District of Columbia, according to research published in the July 24 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
New Guidelines Released for Recovering COVID-19 Patients to Leave Isolation
THURSDAY, July 23, 2020 (HealthDay News) — Many recovering COVID-19 patients in the United States will now be able to leave isolation without further testing to show they are virus-free, the U.S. Centers for Disease Control and Prevention said Wednesday.
Three in Four Americans Favor Face Coverings: Survey
THURSDAY, July 23, 2020 (HealthDay News) — Face coverings should be worn by people when they leave home, three-quarters of Americans say in a new poll.
Most Individuals in U.S. Have Not Been Infected With SARS-CoV-2
THURSDAY, July 23, 2020 (HealthDay News) — During March to early May 2020, most individuals in the United States had not been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), although the estimated number of infections seems to have been much higher than the number of reported cases, according to a study published online July 21 in JAMA Internal Medicine.
Ad5-Vectored COVID-19 Vaccine Immunogenic in Healthy Adults
THURSDAY, July 23, 2020 (HealthDay News) — The nonreplicating adenovirus type-5 (Ad5)-vectored COVID-19 vaccine appears safe and induces immune responses at a dose of 5×1010 viral particles, according to a study published online July 20 in The Lancet.
Role of COVID-19 Treatments Explored in Patients With Cancer
THURSDAY, July 23, 2020 (HealthDay News) — For adults with invasive cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, treatment with hydroxychloroquine in combination with any other drug is associated with increased mortality, according to a study published online July 22 in Cancer Discovery.
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No Spike Seen in Cases of Polio-Like Condition in Children
WEDNESDAY, July 22, 2020 (HealthDay News) — It is not clear if acute flaccid myelitis (AFM) will follow its usual pattern and if we will see a spike of cases in 2020, the U.S. Centers for Disease Control and Prevention says.
U.S. Reaches Deal for Nearly 600 Million Doses of COVID-19 Vaccine
WEDNESDAY, July 22, 2020 (HealthDay News) — A nearly $2 billion contract with pharmaceutical company Pfizer and a German biotechnology firm will provide the United States with up to 600 million doses of a COVID-19 vaccine being developed by the companies, the U.S. government says.
Early Dialysis Does Not Reduce Mortality in Critically Ill With AKI
WEDNESDAY, July 22, 2020 (HealthDay News) — Accelerated initiation of renal-replacement therapy is not associated with a reduced risk for death at 90 days among critically ill patients with acute kidney injury, according to a study published in the July 16 issue of the New England Journal of Medicine.
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Even Mild Obesity Tied to Significantly Worse COVID-19 Outcomes
TUESDAY, July 21, 2020 (HealthDay News) — Obesity is a strong, independent risk factor for poor outcomes among COVID-19 patients, according to a study published July 1 in the European Journal of Endocrinology.
More Online Advance Directives Completed During COVID-19
TUESDAY, July 21, 2020 (HealthDay News) — There has been an increase in completion of advance directives (ADs) during the COVID-19 pandemic, according to a research letter published online July 20 in JAMA Network Open.
Blood Type Not Linked to Progression to Severe COVID-19
TUESDAY, July 21, 2020 (HealthDay News) — For COVID-19 patients, blood type is not associated with the risk for progression to severe disease, according to a study published online July 12 in the Annals of Hematology.
Review: In-ICU Mortality for COVID-19 Down to 41.6 Percent
TUESDAY, July 21, 2020 (HealthDay News) — The in-intensive care unit (ICU) mortality from COVID-19 is lower than initially thought, with a combined mortality of 41.6 percent based on 24 studies, according to a review published online June 30 in Anaesthesia.
Demographic, Clinical, Hospital Factors Tied to COVID-19 Death
MONDAY, July 20, 2020 (HealthDay News) — For COVID-19 patients in the intensive care unit (ICU), demographic, clinical, and hospital-level risk factors are associated with death, according to a study published online July 15 in JAMA Internal Medicine.
Reducing Testing Delay Crucial for Slowing COVID-19 Transmission
Withdrawal From Medetomidine Increasingly Seen in ICUs 
NEWS2 Scores Can ID Patients With Suspected Sepsis Needing Timely Treatment .jpeg)
Flu Treatment With Oseltamivir Linked to Reduced Risk for Pediatric ICU Admissions, Length of Stay 
Therapeutic Hypothermia Duration Explored in Comatose OHCA Survivors 
Autonomous Oxygen Titration Increases Proportion of Time in Normoxemia 
Hypoglossal Nerve Stimulation May Offer Long-Term Cardiovascular Benefits in OSA 
High-Dose Intravenous Vitamin C May Benefit Trauma Patients 
Smartphone-Based Heart Rhythm Monitoring Reduces Same-Day Cancellations 
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