August 2020 Briefing – Pulmonology

Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for August 2020. This roundup includes the latest research news from journal articles, as […]

Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for August 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

AI Model Using Chest X-Ray May Predict 12-Year Lung Cancer Risk

MONDAY, Aug. 31, 2020 (HealthDay News) — A deep learning model based on chest radiograph (CXR) images and data from the electronic medical record (EMR) has better discrimination for smokers at high risk for incident lung cancer than Centers for Medicare & Medicaid Services (CMS) eligibility, according to a study published online Sept. 1 in the Annals of Internal Medicine.

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FDA Could Green-Light COVID-19 Vaccines Before Clinical Trials Completed

MONDAY, Aug. 31, 2020 (HealthDay News) — Emergency use authorization (EUA) or approval for a COVID-19 vaccine before phase 3 clinical trials are complete could be considered by the U.S. Food and Drug Administration, according to the agency’s commissioner, Stephen Hahn, M.D.

CNN Article

Community-Level Factors Explain Some Racial Disparities in COVID-19

MONDAY, Aug. 31, 2020 (HealthDay News) — Community-level factors explain some, but not all, racial and ethnic disparities in COVID-19 rates in Massachusetts, according to a report published online Aug. 27 in Health Affairs.

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Lung-Specific Risk Factors Linked to Hip Fracture in Smokers

MONDAY, Aug. 31, 2020 (HealthDay News) — The addition of lung-specific risk factors into fracture risk assessment tools may more accurately predict hip fracture risk in smokers, according to a study published online Aug. 4 in the Journal of Bone and Mineral Research.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 24 to 28, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Model Says COVID-19 Deaths Could Surpass 317,000 by December

FRIDAY, Aug. 28, 2020 (HealthDay News) — A widely cited model for COVID-19 deaths in the United States predicts a total of 317,000 deaths by December.

CNN Article

Low Rates of Severe Disease, Death Reported for Children With COVID-19

FRIDAY, Aug. 28, 2020 (HealthDay News) — Severe disease and death appear to be rare among children and young people hospitalized with laboratory-confirmed COVID-19, according to an observational study in the United Kingdom published online Aug. 27 in The BMJ.

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Mortality, Intubation Rates Lower With Anticoagulation in COVID-19

FRIDAY, Aug. 28, 2020 (HealthDay News) — Among hospitalized patients with COVID-19, anticoagulation (AC) is associated with reduced mortality and intubation, according to a study published online Aug. 26 in the Journal of the American College of Cardiology.

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Early Use of Empiric Antibacterial Therapy Common in COVID-19

FRIDAY, Aug. 28, 2020 (HealthDay News) — Early empiric antibacterial therapy use is high in patients hospitalized with COVID-19, according to a study published online Aug. 21 in Clinical Infectious Diseases.

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COVID-19 Infection May Initially Present as Acute Pancreatitis

FRIDAY, Aug. 28, 2020 (HealthDay News) — Acute pancreatitis may be a gastrointestinal manifestation of COVID-19, according to research published online Aug. 26 in Gastroenterology.

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Respiratory Disease May Increase Risk for Rheumatoid Arthritis

FRIDAY, Aug. 28, 2020 (HealthDay News) — Respiratory diseases increase the risk for rheumatoid arthritis, according to a study published online Aug. 16 in Arthritis & Rheumatology.

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Maine Summer Camps Identified, Isolated COVID-19 Cases

THURSDAY, Aug. 27, 2020 (HealthDay News) — Three COVID-19-positive people with no symptoms were successfully identified and isolated at four overnight camps in Maine, according to research published in the Aug. 26 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Metabolic Syndrome Linked to Worse Outcomes in COVID-19

THURSDAY, Aug. 27, 2020 (HealthDay News) — Metabolic syndrome (MetS) is associated with a lethal outcome for patients with COVID-19, according to a study published online Aug. 25 in Diabetes Care.

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Changes to CDC COVID-19 Testing Guidelines Trigger Concern

WEDNESDAY, Aug. 26, 2020 (HealthDay News) — Experts are alarmed about revised U.S. Centers for Disease Control and Prevention guidelines advising that people who do not have symptoms of COVID-19 do not need to be tested, even if they have recently been exposed to the new coronavirus.

The New York Times Article

U.S. Nursing Home Staff Must Be Tested Regularly for COVID-19

WEDNESDAY, Aug. 26, 2020 (HealthDay News) — Nursing home staff will have to be tested regularly for COVID-19, and facilities that fail to do so will face fines, the Trump administration said Tuesday.

AP News Article

Exposure to Burning Wood Linked to Abnormal Cardiac Parameters

WEDNESDAY, Aug. 26, 2020 (HealthDay News) — Occupational exposures to burning wood, pesticides, and metals is associated with abnormal parameters of left and right ventricular systolic function, according to a study published online Aug. 26 in the Journal of the American Heart Association.

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Preterm Delivery Ups Risk for Premature Mortality in Mothers

WEDNESDAY, Aug. 26, 2020 (HealthDay News) — Preterm delivery is associated with an increased risk for premature mortality in women, according to a study published online Aug. 19 in The BMJ.

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Increase in Hospital Bed Use Tied to COVID-19 Deaths in Seven Days

WEDNESDAY, Aug. 26, 2020 (HealthDay News) — Intensive care unit (ICU) and non-ICU bed use as a percentage of a state’s hospital bed capacity is significantly associated with an increase in overall COVID-19 deaths during the next seven days, according to a study published online Aug. 19 in the Journal of General Internal Medicine.

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Nurse Understaffing Common in Hospitals Prior to COVID-19

TUESDAY, Aug. 25, 2020 (HealthDay News) — Many hospital nurses in Illinois and New York were burned out and working in understaffed conditions immediately prior to the first wave of COVID-19 patients, according to a study published online Aug. 18 in BMJ Quality & Safety.

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Vitamin D Supplement No Benefit in Pediatric Persistent Asthma

TUESDAY, Aug. 25, 2020 (HealthDay News) — Vitamin D3 supplementation does not prolong the time to severe asthma exacerbation among children with persistent asthma and low vitamin D levels, according to a study published in the Aug. 25 issue of the Journal of the American Medical Association.

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Prevalence of SARS-CoV-2 in Asymptomatic Children Identified

TUESDAY, Aug. 25, 2020 (HealthDay News) — The pooled prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV02) in asymptomatic children is 0.65 percent and is significantly associated with the incidence of COVID-19 in the general population, according to a research letter published online Aug. 25 in JAMA Pediatrics.

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WHO: Plasma Therapy for COVID-19 Still Experimental

TUESDAY, Aug. 25, 2020 (HealthDay News) — The use of blood plasma from COVID-19 survivors to treat patients hospitalized with the disease is still considered experimental, the World Health Organization said the day after the U.S. Food and Drug Administration said it would allow emergency use of the therapy.

AP News Article

Return to Hospital Infrequent After COVID-19 Admission

TUESDAY, Aug. 25, 2020 (HealthDay News) — Return to hospital after discharge for inpatients with COVID-19 is infrequent, according to a study published online Aug. 19 in the Journal of General Internal Medicine.

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Heart Events Observed for ~12 Percent of Adults Hospitalized With Flu

TUESDAY, Aug. 25, 2020 (HealthDay News) — Among adults hospitalized with laboratory-confirmed influenza, 11.7 percent have an acute cardiovascular event, according to a study published online Aug. 25 in the Annals of Internal Medicine.

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Widespread Mask Use Could Save 70,000 U.S. Lives by Dec. 1

MONDAY, Aug. 24, 2020 (HealthDay News) — There could be another 134,000 COVID-19 deaths in the United States by Dec. 1 if no new prevention measures are introduced, and the number of deaths could be much higher if rules are relaxed, researchers report. However, they also said that 70,000 lives could be saved if more people wore masks, CNN reported.

CNN Article

World’s First Confirmed Case of COVID-19 Reinfection Reported in Hong Kong

MONDAY, Aug. 24, 2020 (HealthDay News) — The world’s first confirmed case of reinfection with the new coronavirus has been reported in Hong Kong.

The New York Times Article

Pop Concert Held to Learn More About COVID-19 Spread

MONDAY, Aug. 24, 2020 (HealthDay News) — About 1,500 people attended a pop concert in Germany to help researchers learn how the new coronavirus spreads in such situations.

AP News Article

FDA Approves Wider Use of Plasma as COVID-19 Treatment

MONDAY, Aug. 24, 2020 (HealthDay News) — The U.S. Food and Drug Administration on Sunday cleared the way for more hospitalized COVID-19 patients to be treated with the blood plasma of COVID-19 survivors.

The New York Times Article
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Clinical Impact of Remdesivir in Moderate COVID-19 Unclear

MONDAY, Aug. 24, 2020 (HealthDay News) — Patients with moderate COVID-19 receiving a five-day course of remdesivir have a statistically significant difference in clinical status compared with usual care, according to a study published online Aug. 21 in the Journal of the American Medical Association.

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School-Located Influenza Vaccine Intervention Beneficial

MONDAY, Aug. 24, 2020 (HealthDay News) — A school-located influenza vaccination (SLIV) intervention is associated with a reduction in the incidence of influenza hospitalization, according to a study published online Aug. 18 in PLOS Medicine.

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Black-White Disparity in Lung Cancer Incidence Eliminated

MONDAY, Aug. 24, 2020 (HealthDay News) — The historically higher lung cancer incidence in young Black people compared with White people has disappeared and reversed in men and women, respectively, in the United States, according to a study published online Aug. 20 in JNCI Cancer Spectrum.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 17 to 21, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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White House Blocks FDA’s Power to Regulate Lab Tests

FRIDAY, Aug. 21, 2020 (HealthDay News) — The Trump administration has blocked the U.S. Food and Drug Administration from regulating a wide swath of laboratory tests, including ones for COVID-19.

Washington Post Article

Extract From Deadly Plant Touted as COVID-19 Cure

FRIDAY, Aug. 21, 2020 (HealthDay News) — Experts have slammed claims by a major Trump donor that an extract from a deadly plant is a cure for COVID-19.

The New York Times Article

ACIP Issues Recommendations for 2020 to 2021 Flu Vaccination

FRIDAY, Aug. 21, 2020 (HealthDay News) — Advisory Committee on Immunization Practices (ACIP) recommendations have been updated to include the influenza vaccination for the 2020 to 2021 season; the recommendations were published in the Aug. 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Exposure to Air Pollution Tied to New Asthma in Children

FRIDAY, Aug. 21, 2020 (HealthDay News) — Fine particulate matter contributes to the development of asthma and persistent wheezing in children, according to a study published online Aug. 19 in The BMJ.

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Incidence of COVID-19 Up for American Indians, Alaska Natives

THURSDAY, Aug. 20, 2020 (HealthDay News) — The overall incidence of COVID-19 is increased among American Indian and Alaska Native (AI/AN) persons in the United States, according to research published in the Aug. 19 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Advisory Panel Rejects Nearly All Proposals for Fetal Tissue Research

THURSDAY, Aug. 20, 2020 (HealthDay News) — A Trump administration advisory board to evaluate scientific research involving fetal tissue says 13 of 14 proposals should be rejected.

The New York Times Article

SARS-CoV-2 Nasopharyngeal Load Higher in Children Than Adults

THURSDAY, Aug. 20, 2020 (HealthDay News) — Children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have the highest nasopharyngeal viral load in the first two days of symptoms, according to a study published online Aug. 20 in The Journal of Pediatrics.

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Disparities Seen in COVID-19 Hospitalizations in Racial/Ethnic Subgroups

THURSDAY, Aug. 20, 2020 (HealthDay News) — There are considerable disparities in the prevalence of COVID-19 across racial/ethnic subgroups in the United States, according to a research letter published online Aug. 17 in JAMA Internal Medicine.

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FDA Emergency Approval on Hold for Blood Plasma to Treat COVID-19

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