Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for January 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Rising Temps May Up Burden of Congenital Heart Disease in U.S.
THURSDAY, Jan. 31, 2019 (HealthDay News) — Projected increases in maternal heat exposure may result in increased congenital heart defect (CHD) burden, according to a study published online Jan. 30 in the Journal of the American Heart Association.
FDA Approves First Generic Version of Advair for Asthma, COPD
THURSDAY, Jan. 31, 2019 (HealthDay News) — The first generic form of the Advair Diskus (fluticasone propionate and salmeterol inhalation powder) inhaler has been approved by the U.S. Food and Drug Administration.
More High-Value Care Associated With Receipt of Primary Care
THURSDAY, Jan. 31, 2019 (HealthDay News) — Receipt of primary care is associated with significantly more high-value care, slightly more low-value care, and a better health care experience, according to a study published online Jan. 28 in JAMA Internal Medicine.
Abstract/Full Text (subscription or payment may be required)
Editorial
FDA Receives an ‘F’ in Tobacco Prevention Report Card
WEDNESDAY, Jan. 30, 2019 (HealthDay News) — The U.S. Food and Drug Administration was given an “F” in a new American Lung Association report card evaluating tobacco prevention programs.
CNN Article
State of Tobacco Control
Expanded Recall Announced for Ibuprofen Oral Suspension Drops
WEDNESDAY, Jan. 30, 2019 (HealthDay News) — An expanded recall of ibuprofen oral suspension drops that may contain higher-than-specified levels of ibuprofen that could harm infants’ kidneys has been announced by Tris Pharma, Inc.
More Severe Injuries Sustained at Jump Parks Versus Home Trampolines
WEDNESDAY, Jan. 30, 2019 (HealthDay News) — The proportion of fractures/dislocations, lower-extremity fractures, fractures in adults, and surgical interventions is higher for injuries associated with jump parks versus home trampolines, according to a study published in the Jan. 1 issue of the Journal of the American Academy of Orthopaedic Surgeons.
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No Asthma Benefit Seen With n3PUFA in Overweight Teens
WEDNESDAY, Jan. 30, 2019 (HealthDay News) — Omega-3 fatty acid (n3PUFA) supplements do not appear to improve asthma control in teens and young adults who are overweight or obese, according to a study published online Jan. 25 in the Annals of the American Thoracic Society.
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1976 to 2016 Saw Drop in Firearm Ownership in Families
TUESDAY, Jan. 29, 2019 (HealthDay News) — From 1976 to 2016, there was a decrease in the proportion of families who had young children and owned firearms, although an increase was seen in the proportion who owned handguns, according to a study published online Jan. 28 in Pediatrics.
Prophylaxis for Gonococcal Eye Infections in Newborns Advised
TUESDAY, Jan. 29, 2019 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) has reaffirmed the recommendation for use of ocular prophylaxis for gonococcal ophthalmia neonatorum. This recommendation forms the basis of a final recommendation statement published online Jan. 29 in the Journal of the American Medical Association.
Final Recommendation Statement
Evidence Review (subscription or payment may be required)
Few Patients With Type 1 Diabetes Meeting HbA1c Goals
TUESDAY, Jan. 29, 2019 (HealthDay News) — Only one in five children and adults with type 1 diabetes (T1D) in the United States achieve American Diabetes Association (ADA) goals for glycated hemoglobin (HbA1c), according to a study published online Jan. 18 in Diabetes Technology & Therapeutics.
Washington State Declares Health Emergency as Measles Spreads
MONDAY, Jan. 28, 2019 (HealthDay News) — A statewide public health emergency was declared in Washington after a measles outbreak near Portland, Oregon, reached 31 cases on Friday. The outbreak in the Pacific Northwest is in what has been called an antivaccination “hot spot” in the United States, the Associated Press reported.
Screen Time Linked to Poorer Child Developmental Performance
MONDAY, Jan. 28, 2019 (HealthDay News) — Screen time is associated with poorer performance on developmental screening tests among young children, according to a study published online Jan. 28 in JAMA Pediatrics.
Increase Seen in Multiple-Victim School-Related Homicide Rate
MONDAY, Jan. 28, 2019 (HealthDay News) — During 2009 through 2018, multiple-victim school-associated homicide rates increased significantly, while single-victim homicide rates remained stable from 1994 through 2016, according to research published in the Jan. 25 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
Likelihood of Engaging in Choking Game Higher in Troubled Teens
MONDAY, Jan. 28, 2019 (HealthDay News) — Adolescents with higher levels of conduct disorder symptoms and greater rates of depressive symptoms have increased odds of reporting participation in the choking game, in which pressure is applied to the carotid artery to temporarily limit blood flow and oxygen, according to a study published online Jan. 28 in Pediatrics.
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Adverse Birth Outcomes Up With Medically Assisted Reproduction
MONDAY, Jan. 28, 2019 (HealthDay News) — Children born by medically assisted reproduction have an increased risk for adverse birth outcomes; however, the increased risk appears to be attributable to other factors, according to a study published online Jan. 14 in The Lancet.
Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Lean Body Mass in Childhood Linked to Lung Function at 15
FRIDAY, Jan. 25, 2019 (HealthDay News) — Higher lean body mass during childhood and adolescence is associated with higher lung function at age 15 years for both sexes, according to a study published online Jan. 11 in the American Journal of Respiratory and Critical Care Medicine.
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Psychopathology in Adulthood Up With Child Lead Exposure
THURSDAY, Jan. 24, 2019 (HealthDay News) — Higher childhood blood lead levels are associated with more psychopathology during the life course, according to a study published online Jan. 23 in JAMA Psychiatry.
Improved Genetic Risk Score Aids Type 1 Diabetes Classification
FRIDAY, Jan. 25, 2019 (HealthDay News) — An improved type 1 diabetes (T1D) genetic risk score (GRS), the T1D GRS2, is highly useful for classifying adult incident diabetes type and improving newborn screening, according to a study published in the February issue of Diabetes Care.
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Report IDs Areas Lacking Good Practice in Health Tech Assessment
FRIDAY, Jan. 25, 2019 (HealthDay News) — In a report published in the January issue of Value in Health, an ISPOR–The Professional Society for Health Economics and Outcomes Research working group indicates the lack of good practices in three areas of health technology assessment (HTA).
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Many Teens Not Up to Date on HPV Vaccination
FRIDAY, Jan. 25, 2019 (HealthDay News) — Many adolescents do not complete human papillomavirus (HPV) vaccination before turning 13 or 15 years old, according to a report published online Jan. 17 in the Journal of Infectious Diseases.
Gun Injury Hospitalization Cost Over $911 Million 2010 to 2015
THURSDAY, Jan. 24, 2019 (HealthDay News) — The average annual cost of inpatient hospitalizations for firearm injury exceeded $911 million from 2010 to 2015, with 9.5 percent of that amount due to readmissions, according to a study published online Jan. 24 in PLOS ONE.
Measles Outbreak Prompts Public Emergency in Washington State
THURSDAY, Jan. 24, 2019 (HealthDay News) — An ongoing measles outbreak has led to a public health emergency being declared in Clark County, Washington.
Initiative Tied to Decreased Racial Inequity in Breastfeeding
THURSDAY, Jan. 24, 2019 (HealthDay News) — A hospital-based initiative in Southern states is associated with increases in breastfeeding rates among African-American infants, according to a study published online Jan. 18 in Pediatrics.
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Mavoglurant Improves Visual Attention in Fragile X Syndrome
WEDNESDAY, Jan. 23, 2019 (HealthDay News) — For patients with fragile X syndrome (FXS), mavoglurant treatment improves visual attention and pupil reactivity, according to a study published online Jan. 17 in PLOS ONE.
Herd Protection Seen With 4-Valent HPV Vaccination
WEDNESDAY, Jan. 23, 2019 (HealthDay News) — From 2006 to 2017, there was a decrease in 4-valent vaccine-type human papillomavirus (HPV) detection among vaccinated and unvaccinated women, according to a study published online Jan. 22 in Pediatrics.
Addition of BMT Not Indicated in Some With Peds Hypodiploid ALL
WEDNESDAY, Jan. 23, 2019 (HealthDay News) — For some children with hypodiploid acute lymphoblastic leukemia (ALL), allogeneic hematopoietic cell transplantation does not improve outcomes compared with chemotherapy alone, according to a study published online Jan. 18 in the Journal of Clinical Oncology.
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CDC: Slight Hike in Prevalence of Gastroschisis Since 2006-2010
TUESDAY, Jan. 22, 2019 (HealthDay News) — Over time, the prevalence of gastroschisis has increased, with more babies born with gastroschisis in areas with high and medium versus low opioid prescription rates, according to research published in the Jan. 18 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
FDA Chief Threatens to Halt E-Cigarette Sales
TUESDAY, Jan. 22, 2019 (HealthDay News) — Sales of electronic cigarettes could be halted if companies do not stop marketing the devices to youth, U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D., warned.
Messages for Increasing Parental Confidence in HPV Vaccine ID’d
TUESDAY, Jan. 22, 2019 (HealthDay News) — Providing information on the benefits of vaccination, including cancer prevention, and avoiding expressing urgency to vaccinate can increase parent confidence in human papillomavirus (HPV) vaccination, according to a study published online Jan. 22 in Pediatrics.
Guidelines Developed for Managing Severe Atopic Dermatitis
TUESDAY, Jan. 22, 2019 (HealthDay News) — Guidelines have been developed for the management of severe atopic dermatitis (AD); the recommendations have been published as a clinical management review in the January issue of The Journal of Allergy and Clinical Immunology: In Practice.
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Review Gives Guidance to Support Teens With Gender Dysphoria
TUESDAY, Jan. 22, 2019 (HealthDay News) — Primary care providers are well positioned to provide critical support and personalized care for youth with gender dysphoria and their caregivers or families, according to a review published online Jan. 21 in CMAJ, the journal of the Canadian Medical Association.
Wearable Sensor Data Help ID Children With Internalizing Dx
TUESDAY, Jan. 22, 2019 (HealthDay News) — Wearable sensor data extracted from a fear induction task paired with machine learning can accurately identify young children with internalizing diagnosis, according to a study published online Jan. 16 in PLOS ONE.
Exome Sequencing Beneficial for Pediatric Kidney Recipients
TUESDAY, Jan. 22, 2019 (HealthDay News) — Whole-exome sequencing (WES) can identify a genetic cause for almost one-third of pediatric kidney transplant recipients, according to a study published online Jan. 17 in the Journal of the American Society of Nephrology.
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Assessing Symptoms After 4 Weeks of Psychotherapy Helpful in Teens
FRIDAY, Jan. 18, 2019 (HealthDay News) — Therapists implementing interpersonal psychotherapy for depressed adolescents (IPT-A) should routinely monitor depression symptoms and consider augmenting treatment for insufficient responders as early as week 4 of treatment, according to a study published in the January issue of the Journal of the American Academy of Child & Adolescent Psychiatry.
Mandated Neonatal Abstinence Reporting Helps Quantify Cases
FRIDAY, Jan. 18, 2019 (HealthDay News) — Mandated neonatal abstinence syndrome (NAS) surveillance and reporting allows state health departments to quantify incidence and informs programs and services, according to research published in the Jan. 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
Trained Alert Dogs Can Detect Impending T1DM-Related Events
FRIDAY, Jan. 18, 2019 (HealthDay News) — Trained alert dogs can help patients with type 1 diabetes regulate their blood glucose levels, according to a study published online Jan. 15 in PLOS ONE.
Inappropriate Antibiotic Rx Common in Privately Insured
FRIDAY, Jan. 18, 2019 (HealthDay News) — Less than half of all outpatient antibiotic prescription fills by privately insured nonelderly adults and children in the United States are appropriate or potentially appropriate, according to a study published online Jan. 16 in The BMJ.
FDA Panel Has Tie Vote on New Type 1 Diabetes Drug
FRIDAY, Jan. 18, 2019 (HealthDay News) — A U.S. Food and Drug Administration advisory panel vote on whether to recommend approval of the first oral medication for type 1 diabetes ended in an 8-8 tie Thursday.
FDA Approves First Generic Version of Epilepsy Drug Sabril
THURSDAY, Jan. 17, 2019 (HealthDay News) — The first generic version of Sabril (vigabatrin) has been approved by the U.S. Food and Drug Administration to prevent complex partial seizures in adults and children aged 10 years and older with epilepsy.
WHO: Vaccine Hesitancy a Major Global Health Threat
THURSDAY, Jan. 17, 2019 (HealthDay News) — Vaccine hesitancy is among the top 10 health threats facing the world in 2019, the World Health Organization says.
Newsweek Article
More Information: WHO
FDA Down to 5 Weeks of Funding to Review New Drug Applications
Global Prevalence of Eczema Estimated for Children, Teens 
Immunization Schedule for Children, Teens Updated for 2023 
Most Children Exposed to Makeup, Body Products for Play 
Surge in Severe Strep Cases in Children Was Really a Return to Normal: CDC 
2013 to 2022 Saw Increase in Group A Streptococcal Infections 
Rhinoviruses, Enteroviruses Persisted During Pandemic Among Pediatric Patients 
Genetic, Environmental Prenatal Risk Factors Play Role in Early Atopic Dermatitis 
Measles Outbreak in Ohio Declared Over After 85 Cases 
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