Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for July 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 27 to 31, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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U.S. Puts Up Another $2.1 Billion for Potential COVID-19 Vaccine
FRIDAY, July 31, 2020 (HealthDay News) — The United States is buying up another potential COVID-19 vaccine, the Associated Press reported Friday.
Plenty of COVID-19 Vaccine Coming, Fauci Says
FRIDAY, July 31, 2020 (HealthDay News) — When a COVID-19 vaccine is approved, there should be plenty of it available, Anthony Fauci, M.D., infectious diseases chief at the U.S. National Institutes of Health, told a House panel Friday, the Associated Press reported.
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Johns Hopkins University
Bacterial, Fungal Coinfection Uncommon in COVID-19 Patients
FRIDAY, July 31, 2020 (HealthDay News) — Bacterial and fungal infections are uncommon in hospitalized COVID-19 patients, but coinfection is associated with high mortality and antibiotic use is widespread, according to a study published in the July issue of Infection Control & Hospital Epidemiology.
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FDA Warns Companies Illegally Selling Hangover Cures
THURSDAY, July 30, 2020 (HealthDay News) — The U.S. Food and Drug Administration has sent warning letters to seven companies for illegally selling products they claim will cure, treat, mitigate, or prevent hangovers.
Cinnamon Supplementation May Improve Blood Glucose Control
THURSDAY, July 30, 2020 (HealthDay News) — In individuals with prediabetes, 12 weeks of cinnamon supplementation improved fasting plasma glucose (FPG) and glucose tolerance, according to a study published online July 21 in the Journal of the Endocrine Society.
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Remdesivir Shortages Plague Some Hospitals, Pharmacists Say
THURSDAY, July 30, 2020 (HealthDay News) — One-third of pharmacists say they do not have enough remdesivir to treat all COVID-19 patients who are eligible for it, according to the results of a survey released by the American Society of Health-System Pharmacists (ASHP).
Most Gynecologic Cancer Therapy Not Tied to Higher COVID-19 Risk
THURSDAY, July 30, 2020 (HealthDay News) — For gynecologic oncology patients with COVID-19, the case fatality rate is 14.0 percent, and chemotherapy and recent major surgery do not predict COVID-19 severity or mortality, according to a study published online July 30 in Cancer.
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Nirsevimab Injection Cuts RSV-Linked Infections in Preemies
THURSDAY, July 30, 2020 (HealthDay News) — Nirsevimab prevents respiratory syncytial virus (RSV)-associated lower respiratory tract infections in healthy preterm infants, while maternal RSV fusion (F) protein nanoparticle vaccination did not meet the prespecified criterion for efficacy, according to two studies published in the July 30 issue of the New England Journal of Medicine.
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Teen HPV Vaccination Rates Suboptimal
THURSDAY, July 30, 2020 (HealthDay News) — Lack of parental intent to initiate and complete the human papillomavirus (HPV) vaccine series for adolescents is a major public health concern, according to a study published online July 21 in The Lancet Public Health.
Delayed Treatment of Upper Respiratory Tract Infections Tied to Hospitalization Risk
THURSDAY, July 30, 2020 (HealthDay News) — Delayed treatment of upper respiratory tract infections (URTI) with antibiotics is associated with an increased risk for hospital admissions, according to a study published online June 29 in Clinical Infectious Diseases.
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Low Health Literacy Tied to Worse Heart Failure Outcomes
WEDNESDAY, July 29, 2020 (HealthDay News) — Poor health literacy is associated with worse heart failure outcomes, according to a review published in the June issue of JACC: Heart Failure.
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SGLT-2 Inhibitors May Raise Risk for Diabetic Ketoacidosis
WEDNESDAY, July 29, 2020 (HealthDay News) — In patients with type 2 diabetes, sodium-glucose cotransporter-2 (SGLT-2) inhibitors are associated with an increased risk for diabetic ketoacidosis (DKA), according to a study published online July 28 in the Annals of Internal Medicine.
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Cost-Sharing Caps for Insulin Would Benefit Youth With T1D
WEDNESDAY, July 29, 2020 (HealthDay News) — For privately insured young children and adults with type 1 diabetes, the mean annual out-of-pocket spending on insulin was $494 in 2018, and many would benefit from price caps, according to a research letter published online July 27 in JAMA Pediatrics.
Relapses Linked to Accelerated Disability Progression in SPMS
TUESDAY, July 28, 2020 (HealthDay News) — For patients with secondary progressive multiple sclerosis (SPMS), relapses are associated with accelerated disability progression, according to a study published online July 27 in JAMA Neurology.
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Increase Found in Suicide-Related Exposure Rates to OTC Analgesics
TUESDAY, July 28, 2020 (HealthDay News) — There has been a recent increase in suicide-related exposure rates to over-the-counter (OTC) analgesics, according to a study published online July 26 in Pharmacoepidemiology & Drug Safety.
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FDA Warns Again About Dangers of Methanol-Based Hand Sanitizers
TUESDAY, July 28, 2020 (HealthDay News) — The U.S. Food and Drug Administration is warning consumers not to use alcohol-based hand sanitizers containing methanol, or wood alcohol, which is used in fuel and antifreeze and is toxic if absorbed through the skin or life-threatening if ingested.
Vertebral Fractures Up With Long-Term Delay of Denosumab
TUESDAY, July 28, 2020 (HealthDay News) — Compared with on-time dosing, delay of denosumab by more than 16 weeks is associated with an increased risk for vertebral fractures, according to a study published online July 28 in the Annals of Internal Medicine.
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Postmarketing Surveillance Helps Identify Vaccine Safety Issues
TUESDAY, July 28, 2020 (HealthDay News) — A review of all safety-related labeling changes for FDA-approved vaccines during a 20-year period shows vaccines are largely safe, and many of the safety issues are identified through postmarketing surveillance, according to a study published online July 28 in the Annals of Internal Medicine.
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NSAID Use Linked to Cardiovascular, Bleeding Events Post-MI
MONDAY, July 27, 2020 (HealthDay News) — For patients with myocardial infarction (MI), nonsteroidal anti-inflammatory drug (NSAID) treatment is associated with a significantly increased risk for cardiovascular and bleeding events, according to a study published in the Aug. 4 issue of the Journal of the American College of Cardiology.
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COVID-19 Vaccine Candidate Now in Final Phase Testing
MONDAY, July 27, 2020 (HealthDay News) — A vaccine developed by the U.S. National Institutes of Health and Moderna has entered the final phase of testing, the Associated Press reported Monday.
Large Proportion of COVID-19 Studies Have Low-Level Evidence
MONDAY, July 27, 2020 (HealthDay News) — A large proportion of studies on COVID-19 have a low level of evidence, according to a research letter published online July 27 in JAMA Internal Medicine.
Impact on Glucocorticoids in COVID-19 Varies With CRP Levels
MONDAY, July 27, 2020 (HealthDay News) — The impact of glucocorticoid treatment on patients with COVID-19 varies according to C-reactive protein (CRP) levels, according to a study published online July 22 in the Journal of Hospital Medicine.
Spine Surgery Patients Prescribed the Most Postoperative Narcotics
MONDAY, July 27, 2020 (HealthDay News) — Spine surgery patients are prescribed the most narcotics in the three months following surgery, and patient-reported pain at hospital discharge is associated with increased narcotic use in this period, according to a study published in the July 1 issue of the Journal of the American Academy of Orthopaedic Surgeons.
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FDA: Doctors Should Discuss Opioid OD Antidote With Patients
FRIDAY, July 24, 2020 (HealthDay News) — Doctors should tell patients and caregivers about the overdose antidote naloxone when they prescribe opioid painkillers such as Percocet and OxyContin and medicines to treat opioid addiction, including buprenorphine, methadone, and naltrexone, the U.S. Food and Drug Administration said Thursday.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 20 to 24, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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CDC Guidance Issued for Testing, Management of HCP Exposed to Hep C
FRIDAY, July 24, 2020 (HealthDay News) — In a U.S. Centers for Disease Control and Prevention guidance report, published in the July 24 issue of Morbidity and Mortality Weekly Report, recommendations are presented for testing and clinical management of health care personnel (HCP) exposed to the hepatitis C virus (HCV).
Chimpanzee Adenovirus-Vectored Vaccine Promising for COVID-19
FRIDAY, July 24, 2020 (HealthDay News) — A chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein has acceptable safety and induces antibody and T-cell immune responses, according to a study published online July 20 in The Lancet.
Financial Health of Hospitals ‘Dire’ Due to COVID-19
THURSDAY, July 23, 2020 (HealthDay News) — COVID-19 continues to cause financial peril for U.S. hospitals, according to a report released by the American Hospital Association (AHA).
Ad5-Vectored COVID-19 Vaccine Immunogenic in Healthy Adults
THURSDAY, July 23, 2020 (HealthDay News) — The nonreplicating adenovirus type-5 (Ad5)-vectored COVID-19 vaccine appears safe and induces immune responses at a dose of 5×1010 viral particles, according to a study published online July 20 in The Lancet.
Role of COVID-19 Treatments Explored in Patients With Cancer
THURSDAY, July 23, 2020 (HealthDay News) — For adults with invasive cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, treatment with hydroxychloroquine in combination with any other drug is associated with increased mortality, according to a study published online July 22 in Cancer Discovery.
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Varenicline Strongly Recommended for Smoking Cessation
THURSDAY, July 23, 2020 (HealthDay News) — Varenicline is strongly recommended over the patch for adult smokers hoping to quit, according to an American Thoracic Society practice guideline published online in the July 15 issue of the American Journal of Respiratory and Critical Care Medicine.
U.S. Reaches Deal for Nearly 600 Million Doses of COVID-19 Vaccine
WEDNESDAY, July 22, 2020 (HealthDay News) — A nearly $2 billion contract with pharmaceutical company Pfizer and a German biotechnology firm will provide the United States with up to 600 million doses of a COVID-19 vaccine being developed by the companies, the U.S. government says.
Pembrolizumab Use Supported in Advanced Melanoma
WEDNESDAY, July 22, 2020 (HealthDay News) — Use of pembrolizumab is supported among patients with advanced melanoma, regardless of BRAF V600E/K mutation status or prior receipt of a BRAF inhibitor (BRAFi) with or without MEK inhibitor (MEKi) therapy, according to a study published online July 20 in JAMA Oncology.
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Some With Opioid Use Disorder Rejected From Post-Acute Care
WEDNESDAY, July 22, 2020 (HealthDay News) — Individuals hospitalized with opioid use disorder (OUD) frequently experience explicit discrimination when being rejected from post-acute care, according to a study published online July 15 in the Journal of Addiction Medicine.
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Parents Make Some Common Sunscreen Mistakes
TUESDAY, July 21, 2020 (HealthDay News) — Some parents may not be adequately protecting their children from the sun, according to a new C.S. Mott Children’s Hospital national poll from the University of Michigan in Ann Arbor.
U.K. Study Looks at Stepping Down Meds in Stable Asthma
TUESDAY, July 21, 2020 (HealthDay News) — Asthma patients are increasingly prescribed higher levels of treatment, and few patients step down medications, according to a study published online July 21 in PLOS Medicine.
Recommendations Updated for Barrier Method Use Among Teens
Homicide, Suicide, and Overdose Leading Causes of Maternal Death 
Model Predicts Poor Outcomes Within 30 Days of a Before Medically Advised Discharge 
Fewer Than Half of Drug Overdose Survivors Go to the Hospital 
2000 to 2023 Saw Rise in Pediatric Exposure to Medications, Supplements 
2013 to 2024 Saw Decrease in Benzodiazepine Prescribing 
GLP-1 Receptor Agonists, SGLT-2is Slow Renal Function Decline in T2D With Albuminuria 
Polypharmacy of Prescription Medications Increased for U.S. Older Adults 
Low Hydroxychloroquine Intake, Blood Levels Linked to ASCVD Risk in Lupus 
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