Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for June 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Brain Iron Concentrations Increased in Alzheimer Disease
TUESDAY, June 30, 2020 (HealthDay News) — Patients with Alzheimer disease (AD) have increased iron concentration in the deep gray matter and neocortical regions compared with healthy controls (HC), according to a study published online June 30 in Radiology.
FBI Warns of Scammers Selling Fake COVID-19 Antibody Tests
TUESDAY, June 30, 2020 (HealthDay News) — Fake or unapproved COVID-19 antibody tests are being sold by scammers, the Federal Bureau of Investigation warns.
U.S. Could See 100,000 New Cases of COVID-19 Each Day, Fauci Says
TUESDAY, June 30, 2020 (HealthDay News) — Top U.S. infectious disease expert Anthony Fauci, M.D., warned Congress on Tuesday that COVID-19 infections could climb to 100,000 new cases daily unless ongoing outbreaks are contained.
Comparative Effectiveness of Treatments Explored in T2DM
TUESDAY, June 30, 2020 (HealthDay News) — For patients with type 2 diabetes at low cardiovascular risk, there are no differences in vascular outcomes between treatments, according to research published online June 30 in the Annals of Internal Medicine.
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COVID-19 Drug Remdesivir Could Cost Up to $3,120 Per Patient
MONDAY, June 29, 2020 (HealthDay News) — Gilead Sciences, the maker of remdesivir, the first drug that showed promise in treating COVID-19 infections, will charge U.S. hospitals $3,120 for a patient with private insurance, the company announced Monday.
Incidence of VTE, Major Bleeding High in Primary CNS Lymphoma
MONDAY, June 29, 2020 (HealthDay News) — The incidence of venous thromboembolism (VTE) and major bleeding is high among patients with primary central nervous system lymphoma (PCNSL), according to a study published online June 23 in Leukemia & Lymphoma.
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Trump Administration Asks Supreme Court to Overturn Affordable Care Act
FRIDAY, June 26, 2020 (HealthDay News) — The Trump administration has asked the Supreme Court to overturn the Affordable Care Act (ACA).
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 22 to 26, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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U.S. Has Second Day of Record Rise in COVID-19 Cases; Young People Fueling Trend
FRIDAY, June 26, 2020 (HealthDay News) — As the United States reported yet another record-breaking number of COVID-19 cases on Thursday, public health officials warned that younger Americans now account for an ever-growing percentage of infections.
Colchicine May Improve Time to Clinical Deterioration in COVID-19
FRIDAY, June 26, 2020 (HealthDay News) — Hospitalized patients with COVID-19 receiving colchicine have significantly improved time to clinical deterioration, according to a study published online June 24 in JAMA Network Open.
ED Visits for Childhood Asthma Down During Pandemic
FRIDAY, June 26, 2020 (HealthDay News) — There has been a dramatic decrease in pediatric asthma-related emergency department use during the COVID-19 pandemic compared to the four previous years, according to research published online June 6 in the Journal of Allergy and Clinical Immunology: In Practice.
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Texas Pauses Reopening as COVID-19 Cases Rise
THURSDAY, June 25, 2020 (HealthDay News) — As COVID-19 cases surge in Texas, the state is pausing its reopening process and freeing up hospital beds for COVID-19 patients.
Congo Marks End of World’s Second Deadliest Ebola Outbreak
THURSDAY, June 25, 2020 (HealthDay News) — The end of the second deadliest Ebola outbreak in history was officially marked Thursday by the Democratic Republic of Congo.
Contraceptives Beneficial for Premature Ovarian Insufficiency
THURSDAY, June 25, 2020 (HealthDay News) — For women with premature ovarian insufficiency (POI), continuous use of combined oral contraceptives (COC) is associated with increased bone mineral density (BMD), similar to that seen with high-dose hormone therapy (HT), according to a study published online June 22 in Menopause.
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Allopurinol Does Not Affect eGFR in Chronic Kidney Disease
THURSDAY, June 25, 2020 (HealthDay News) — Allopurinol does not affect estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease and does not result in a clinically meaningful benefit in kidney outcomes from serum urate reduction among patients with type 1 diabetes and early-to-moderate diabetic kidney disease, according to two studies published in the June 25 issue of the New England Journal of Medicine.
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Inhibition of Sclerostin May Increase Cardiovascular Risk
THURSDAY, June 25, 2020 (HealthDay News) — Inhibition of sclerostin with romosozumab may increase cardiovascular risk, according to research published in the June 24 issue of Science Translational Medicine.
Model May Help Predict Risk for Testing Positive for COVID-19
THURSDAY, June 25, 2020 (HealthDay News) — It is possible to predict the likelihood of testing positive for COVID-19, according to a study published online June 10 in CHEST.
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Triple Inhaled Therapy Aids in Moderate-to-Very Severe COPD
THURSDAY, June 25, 2020 (HealthDay News) — Triple therapy, including glucocorticoid at either of two dose levels, is beneficial for moderate-to-very severe chronic obstructive pulmonary disease (COPD), according to a study published online June 24 in the New England Journal of Medicine.
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Administrative Data Predict Mortality With Diabetes
THURSDAY, June 25, 2020 (HealthDay News) — Factors readily available in administrative data can predict five- and 10-year mortality in older adults with diabetes, according to a study published online June 19 in Diabetes Care.
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Sanofi Speeds COVID-19 Vaccine Efforts
WEDNESDAY, June 24, 2020 (HealthDay News) — French drugmaker Sanofi has shortened its timeline to get a COVID-19 vaccine on the market.
J&J Ordered to Pay $2.1 Billion in Talcum Product Lawsuit
WEDNESDAY, June 24, 2020 (HealthDay News) — Johnson & Johnson and a subsidiary must pay $2.1 billion in damages to women who said their ovarian cancers were caused by the company’s baby powder and other talcum products, a Missouri appeals court ruled Tuesday.
CDC: 10.7 Percent of U.S. Adults Used Rx Pain Meds in 2015 to 2018
WEDNESDAY, June 24, 2020 (HealthDay News) — In 2015 to 2018, 10.7 percent of U.S. adults aged 20 years or older used one or more prescription pain medications in the previous 30 days, according to a June data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.
Tocilizumab Shows Promise for Treatment of COVID-19
WEDNESDAY, June 24, 2020 (HealthDay News) — Use of tocilizumab to target cytokine release syndrome (CRS) seems beneficial for patients with COVID-19, according to a study published online June 15 in CHEST.
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COVID-19 Vaccine May Be Available by Late 2020, Early 2021: Fauci
TUESDAY, June 23, 2020 (HealthDay News) — There could be a COVID-19 vaccine by the end of this year or early next year, according to Anthony Fauci, M.D., infectious diseases chief at the U.S. National Institutes of Health.
African-American Participation Inadequate in Cancer Drug Trials
TUESDAY, June 23, 2020 (HealthDay News) — African-Americans are underrepresented in clinical trials leading to approval of cancer medications, according to a research letter published online June 23 in the Annals of Internal Medicine.
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COVID-19 Hospitalization Up With Prednisone in Rheumatic Disease
TUESDAY, June 23, 2020 (HealthDay News) — For patients with rheumatic disease with COVID-19, glucocorticoids are associated with increased odds of hospitalization, according to a study published in the July issue of the Annals of Rheumatic Diseases.
Nephrogenic Systemic Fibrosis Rare With Newer GBCA Exposure
TUESDAY, June 23, 2020 (HealthDay News) — The occurrence of nephrogenic systemic fibrosis (NSF) appears to be rare after exposure to newer gadolinium-based contrast agents (GBCA), according to a review published online June 23 in the Annals of Internal Medicine.
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Small Increase Seen in Risk for Subdeltoid Bursitis With Flu Shot
TUESDAY, June 23, 2020 (HealthDay News) — There is a small increased risk for subdeltoid bursitis after influenza vaccination, according to a study published online June 23 in the Annals of Internal Medicine.
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Inhaled Remdesivir May Allow COVID-19 Patients to Be Treated at Home
MONDAY, June 22, 2020 (HealthDay News) — An inhaled version of the antiviral drug remdesivir will soon be tested outside a hospital setting, Gilead Sciences announced Monday.
Children’s Robitussin Honey Cough and Chest Congestion DM Recalled
MONDAY, June 22, 2020 (HealthDay News) — Two lots of Children’s Robitussin Honey Cough and Chest Congestion DM and one lot of Children’s Dimetapp Cold and Cough have been recalled because they have incorrect dosing cups that could put children at risk for an overdose.
NIH Stops Hydroxychloroquine Trial
MONDAY, June 22, 2020 (HealthDay News) — The National Institutes of Health announced Saturday that a clinical trial evaluating hydroxychloroquine for the treatment of COVID-19 has been stopped because the drug likely provides no benefit.
Tanezumab Improves Pain, Function in Chronic Low Back Pain
MONDAY, June 22, 2020 (HealthDay News) — For patients with chronic low back pain, tanezumab 10 mg significantly improves pain and function, according to a study published online June 19 in PAIN.
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Vitamin D May Cut Colitis Risk for Immune Checkpoint Inhibitors
MONDAY, June 22, 2020 (HealthDay News) — For patients with melanoma treated with immune checkpoint inhibitors (ICIs), vitamin D intake is associated with a reduced risk for ICI colitis, according to a study published online June 22 in Cancer.
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Poll: Parents Most Concerned About Diseases From Tick Bites
FRIDAY, June 19, 2020 (HealthDay News) — Parents are more concerned about diseases from tick bites than from mosquito bites, according to a new C.S. Mott Children’s Hospital national poll from the University of Michigan in Ann Arbor.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 15 to 19, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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Life Expectancy Gap Closing for Patients With HIV
FRIDAY, June 19, 2020 (HealthDay News) — Life expectancy of adults with HIV infection is nearing that of individuals without HIV infection, according to a study published online June 15 in JAMA Network Open.
Multilevel Interventions May Boost HPV Vaccination Rates
FRIDAY, June 19, 2020 (HealthDay News) — Multilevel, provider-oriented interventions may improve human papillomavirus (HPV) vaccine series initiation and completion, according to a study published in the June 1 issue of Pediatrics.
Cardioprotective Therapy Use Lower With Cancer History
THURSDAY, June 18, 2020 (HealthDay News) — Cardioprotective therapies, especially statins and antiplatelets, are underutilized in patients with a history of cancer (CaHx), according to a research letter published in the June 1 issue of JACC: CardioOncology.
Court Rules Against Drug Price Disclosures in TV Ads
THURSDAY, June 18, 2020 (HealthDay News) — The U.S. government does not have the legal authority to force drug companies to disclose prices in their TV ads, a federal appeals court says.
Nine Texas Mayors Ask Governor for Power to Mandate Face Masks
THURSDAY, June 18, 2020 (HealthDay News) — Mayors in Houston, Dallas, Austin, San Antonio, and five other Texas municipalities want Gov. Greg Abbott to give them the power to require people to wear masks in public “where physical distancing cannot be practiced.”
Face-Mask Use May Mitigate Spread of COVID-19
THURSDAY, June 18, 2020 (HealthDay News) — Requiring face-mask use in public may help to mitigate the spread of COVID-19, according to a report published online June 16 in Health Affairs.
Homicide, Suicide, and Overdose Leading Causes of Maternal Death 
Model Predicts Poor Outcomes Within 30 Days of a Before Medically Advised Discharge 
Fewer Than Half of Drug Overdose Survivors Go to the Hospital 
2000 to 2023 Saw Rise in Pediatric Exposure to Medications, Supplements 
2013 to 2024 Saw Decrease in Benzodiazepine Prescribing 
GLP-1 Receptor Agonists, SGLT-2is Slow Renal Function Decline in T2D With Albuminuria 
Polypharmacy of Prescription Medications Increased for U.S. Older Adults 
Low Hydroxychloroquine Intake, Blood Levels Linked to ASCVD Risk in Lupus 
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