Declines in global cognition and executive function significantly faster for women, despite higher baseline performance
FRIDAY, March 12, 2021 (HealthDay News) — Older women may have greater cognitive reserve but faster cognitive decline than men, according to a study published online Feb. 25 in JAMA Network Open.
Deborah A. Levine, M.D., from the University of Michigan in Ann Arbor, and colleagues assessed the relationship between sex and cognitive decline to better understand sex differences in dementia risk using pooled data from five cohort studies (1971 to 2017; 26,088 participants; median follow-up, 7.9 years).
The researchers found that women had significantly higher baseline performance than men in global cognition (2.20 points higher), executive function (2.13 points higher), and memory (1.89 points higher). However, women had significantly faster declines in global cognition (–0.07 points per year faster) and executive function (–0.06 points per year faster) than men. Declines in memory were similar between men and women.
“Our findings suggest that women are at risk for delayed identification of cognitive decline, yet more rapid trajectory of decline, suggesting increased risk of dementia and disability compared with men, consistent with research showing that women with mild cognitive impairment or Alzheimer disease have faster cognitive decline than men,” the authors write.
Prep for Conservative Management, Dialysis Yield Similar Results in Older Patients With Kidney Failure 
Study Looks at Approaches to Prescribing Obesity Medications for Older Adults 
CTE Pathology Found in Nearly 75 Percent of Deceased Former NFL Players .jpg)
Recurrent Visual Field Progression Happens for 1 in 4 With Glaucoma 
Statin Use Linked to Lower Risk for Glaucoma Incidence 
Lower Cognitive Functioning During 60s Linked to Subsequent Stroke Risk 
Ambient Temperature Linked to Intraocular Pressure in Glaucoma 
Polypharmacy of Prescription Medications Increased for U.S. Older Adults 
