Each daily consumption of 12 g alcohol increases risk for cirrhosis by 6.2 percent, hepatocellular carcinoma by 11.5 percent
WEDNESDAY, Jan. 29, 2025 (HealthDay News) — For patients with hepatitis B virus, alcohol is associated with dose-dependent increased risks for cirrhosis and hepatocellular carcinoma (HCC), according to a review published online Jan. 21 in the Journal of Clinical and Translational Hepatology.
Yin-Ping Wu, from the Qilu University Hospital of Shandong University in Jinan, China, and colleagues pooled data on the incidence of cirrhosis and HCC and developed a dose-dependent model of the effect of alcohol on cirrhosis and HCC. Data were included for 33,272 patients with hepatitis B virus from 45 studies.
The researchers found that the overall pooled odds ratios were 2.27 and 2.61 for cirrhosis and HCC, respectively, among drinkers versus nondrinkers. Compared with low-level drinkers, high-level drinkers had estimated pooled odds ratios of 2.34 and 2.42 for cirrhosis and HCC, respectively. A linear dose-dependent analysis showed that each daily consumption of 12 g of alcohol increased the risks for cirrhosis and HCC by 6.2 and 11.5 percent, respectively.
“Our meta-analysis is the first report to show that alcohol consumption increases the risk of cirrhosis and HCC in patients with HBV infection in a dose-dependent manner,” the authors write.
Steatotic Liver Disease Risk Scores Compared for Predicting Cirrhosis 
Cirrhosis Can Recur After Liver Transplant 
Genetics, Diabetes Tied to MASLD-Associated Cirrhosis Before Age 50 
Alcohol-Attributable Cancer Mortality Has Increased Significantly in the U.S. 
Active Smoking Linked to Progression of Sickle Cell Retinopathy .jpg)
Most Specialty Oral Anticancer Meds for Blood Cancers Are Initially Rejected by Insurers 
Personalized Support Boosts Families" Genetic Testing for Hereditary Cancers 
Gap Found Between Awareness of Breast Cancer Risk and Risk-Reducing Behavior 
