Here are what the editors at HealthDay consider to be the most important developments in Pathology for August 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
FDA Could Green-Light COVID-19 Vaccines Before Clinical Trials Completed
MONDAY, Aug. 31, 2020 (HealthDay News) — Emergency use authorization (EUA) or approval for a COVID-19 vaccine before phase 3 clinical trials are complete could be considered by the U.S. Food and Drug Administration, according to the agency’s commissioner, Stephen Hahn, M.D.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 24 to 28, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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Model Says COVID-19 Deaths Could Surpass 317,000 by December
FRIDAY, Aug. 28, 2020 (HealthDay News) — A widely cited model for COVID-19 deaths in the United States predicts a total of 317,000 deaths by December.
Proteomic Markers May Predict Psychosis in Those at Risk
FRIDAY, Aug. 28, 2020 (HealthDay News) — In young people at risk for psychosis, proteomic biomarkers may help to individualize prognosis, according to a study published online Aug. 26 in JAMA Psychiatry.
Low Rates of Severe Disease, Death Reported for Children With COVID-19
FRIDAY, Aug. 28, 2020 (HealthDay News) — Severe disease and death appear to be rare among children and young people hospitalized with laboratory-confirmed COVID-19, according to an observational study in the United Kingdom published online Aug. 27 in The BMJ.
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COVID-19 Infection May Initially Present as Acute Pancreatitis
FRIDAY, Aug. 28, 2020 (HealthDay News) — Acute pancreatitis may be a gastrointestinal manifestation of COVID-19, according to research published online Aug. 26 in Gastroenterology.
Many Opt for Genetic Testing of Embryos for Kidney Disease
FRIDAY, Aug. 28, 2020 (HealthDay News) — About half of couples referred for counseling due to a family history of kidney disease opt for preimplantation genetic testing for monogenic kidney disease, and 65 percent of those experience one or more live births of an unaffected child, according to a study published online Aug. 27 in the Clinical Journal of the American Society of Nephrology.
Respiratory Disease May Increase Risk for Rheumatoid Arthritis
FRIDAY, Aug. 28, 2020 (HealthDay News) — Respiratory diseases increase the risk for rheumatoid arthritis, according to a study published online Aug. 16 in Arthritis & Rheumatology.
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Maine Summer Camps Identified, Isolated COVID-19 Cases
THURSDAY, Aug. 27, 2020 (HealthDay News) — Three COVID-19-positive people with no symptoms were successfully identified and isolated at four overnight camps in Maine, according to research published in the Aug. 26 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
Smoking, High Early-Life BMI Projected to Add to MS Burden
THURSDAY, Aug. 27, 2020 (HealthDay News) — The combined estimated multiple sclerosis (MS) population-attributable fractions (PAFs) for smoking and childhood and adolescent high body mass index (BMI) vary from 11 to 14 percent in conservative estimates, according to a study published online Aug. 26 in the International Journal of Epidemiology.
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WHO: Polio Eradicated in Africa
WEDNESDAY, Aug. 26, 2020 (HealthDay News) — An effort that began in 1996 has led to the eradication of polio in Africa, according to the World Health Organization.
Changes to CDC COVID-19 Testing Guidelines Trigger Concern
WEDNESDAY, Aug. 26, 2020 (HealthDay News) — Experts are alarmed about revised U.S. Centers for Disease Control and Prevention guidelines advising that people who do not have symptoms of COVID-19 do not need to be tested, even if they have recently been exposed to the new coronavirus.
U.S. Nursing Home Staff Must Be Tested Regularly for COVID-19
WEDNESDAY, Aug. 26, 2020 (HealthDay News) — Nursing home staff will have to be tested regularly for COVID-19, and facilities that fail to do so will face fines, the Trump administration said Tuesday.
Prevalence of SARS-CoV-2 in Asymptomatic Children Identified
TUESDAY, Aug. 25, 2020 (HealthDay News) — The pooled prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV02) in asymptomatic children is 0.65 percent and is significantly associated with the incidence of COVID-19 in the general population, according to a research letter published online Aug. 25 in JAMA Pediatrics.
Care Delayed for Many U.S. Breast Cancer Patients Early in Pandemic
TUESDAY, Aug. 25, 2020 (HealthDay News) — Nearly half of breast cancer patients have experienced delays in care due to the COVID-19 pandemic, according to a study published online Aug. 9 in Breast Cancer Research and Treatment.
Pop Concert Held to Learn More About COVID-19 Spread
MONDAY, Aug. 24, 2020 (HealthDay News) — About 1,500 people attended a pop concert in Germany to help researchers learn how the new coronavirus spreads in such situations.
Widespread Mask Use Could Save 70,000 U.S. Lives by Dec. 1
MONDAY, Aug. 24, 2020 (HealthDay News) — There could be another 134,000 COVID-19 deaths in the United States by Dec. 1 if no new prevention measures are introduced, and the number of deaths could be much higher if rules are relaxed, researchers report. However, they also said that 70,000 lives could be saved if more people wore masks, CNN reported.
World’s First Confirmed Case of COVID-19 Reinfection Reported in Hong Kong
MONDAY, Aug. 24, 2020 (HealthDay News) — The world’s first confirmed case of reinfection with the new coronavirus has been reported in Hong Kong.
p16INK4a Expression Increased in Young Cancer Survivors
MONDAY, Aug. 24, 2020 (HealthDay News) — Pediatric and young adult cancer survivors, frail versus robust survivors, and newly diagnosed pediatric patients after cancer therapy have increased expression of p16INK4a, corresponding with age acceleration, according to a study published online Aug. 24 in Cancer.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 17 to 21, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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White House Blocks FDA’s Power to Regulate Lab Tests
FRIDAY, Aug. 21, 2020 (HealthDay News) — The Trump administration has blocked the U.S. Food and Drug Administration from regulating a wide swath of laboratory tests, including ones for COVID-19.
Extract From Deadly Plant Touted as COVID-19 Cure
FRIDAY, Aug. 21, 2020 (HealthDay News) — Experts have slammed claims by a major Trump donor that an extract from a deadly plant is a cure for COVID-19.
Advisory Panel Rejects Nearly All Proposals for Fetal Tissue Research
THURSDAY, Aug. 20, 2020 (HealthDay News) — A Trump administration advisory board to evaluate scientific research involving fetal tissue says 13 of 14 proposals should be rejected.
Incidence of COVID-19 Up for American Indians, Alaska Natives
THURSDAY, Aug. 20, 2020 (HealthDay News) — The overall incidence of COVID-19 is increased among American Indian and Alaska Native (AI/AN) persons in the United States, according to research published in the Aug. 19 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
Genetically Modified Mosquitoes to Be Released in Florida Keys
THURSDAY, Aug. 20, 2020 (HealthDay News) — Hundreds of millions of genetically modified mosquitoes will be released into the Florida Keys to test if they can help control Aedes aegypti mosquitoes that carry several deadly diseases, including Zika, dengue, chikungunya, and yellow fever.
Michigan to Pay $600 Million to Flint Water Crisis Victims
THURSDAY, Aug. 20, 2020 (HealthDay News) — Victims of the Flint water crisis will receive about $600 million from the state of Michigan in a major settlement to be announced this week, two people with knowledge of the deal say.
Relationship Between Alzheimer Disease, Sleep Patterns Explored
THURSDAY, Aug. 20, 2020 (HealthDay News) — Alzheimer disease (AD) may causally influence sleep patterns, but these patterns do not have a causal role in AD, according to a study published online Aug. 19 in Neurology.
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Antibiotic Exposure Linked to Risk for Inflammatory Bowel Disease
THURSDAY, Aug. 20, 2020 (HealthDay News) — Higher cumulative exposure to antibiotics is associated with an increased risk for new-onset inflammatory bowel disease (IBD), according to a study published online Aug. 17 in The Lancet Gastroenterology & Hepatology.
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SARS-CoV-2 Nasopharyngeal Load Higher in Children Than Adults
THURSDAY, Aug. 20, 2020 (HealthDay News) — Children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have the highest nasopharyngeal viral load in the first two days of symptoms, according to a study published online Aug. 20 in The Journal of Pediatrics.
Disparities Seen in COVID-19 Hospitalizations in Racial/Ethnic Subgroups
THURSDAY, Aug. 20, 2020 (HealthDay News) — There are considerable disparities in the prevalence of COVID-19 across racial/ethnic subgroups in the United States, according to a research letter published online Aug. 17 in JAMA Internal Medicine.
FDA: COVID-19 Test Could Give Inaccurate Results
TUESDAY, Aug. 18, 2020 (HealthDay News) — A widely used COVID-19 test could produce inaccurate results due to issues with the equipment and software used to run the test, the U.S. Food and Drug Administration warned Monday.
Higher BPA Exposure Linked to Increased Risk for All-Cause Mortality
TUESDAY, Aug. 18, 2020 (HealthDay News) — Higher bisphenol A (BPA) exposure is associated with an increased risk for all-cause mortality in a nationally representative cohort of U.S. adults, according to a study published online Aug. 17 in JAMA Network Open.
COVID-19 Antibodies Detected in Maternity Care Workers in U.K.
TUESDAY, Aug. 18, 2020 (HealthDay News) — One out of six maternity health care workers are seropositive for antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a study published online Aug. 10 in Anaesthesia.
Neck Gaiters ‘Worse Than Nothing’ in Preventing COVID-19 Spread
MONDAY, Aug. 17, 2020 (HealthDay News) — Thin, stretchy neck gaiters are “worse than nothing” when it comes to preventing the spread of COVID-19, according to researchers.
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COVID-19 Impact on Homeless People in U.S. Not as Bad as Feared
MONDAY, Aug. 17, 2020 (HealthDay News) — The impact of the COVID-19 pandemic on homeless people in the United States has not been as severe as feared, data show.
Factors Tied to Hormone Therapy Use After Oophorectomy ID’d
MONDAY, Aug. 17, 2020 (HealthDay News) — Age at surgery, education level, and preventive mastectomy are associated with hormone therapy (HT) use after preventive oophorectomy in BRCA mutation carriers, according to a study published online Aug. 10 in Menopause.
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Guidance Issued for Genetic Testing in Prostate Cancer
MONDAY, Aug. 17, 2020 (HealthDay News) — As a result of the Philadelphia Prostate Cancer Consensus Conference, hosted by Sidney Kimmel Cancer Center-Jefferson Health and the Department of Urology at Jefferson, recommendations have been developed for implementing germline testing for prostate cancer. The consensus framework was recently published in the Journal of Clinical Oncology.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 10 to 14, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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Excess Mortality During Peak of 1918 Flu Similar to COVID-19 in NYC
FRIDAY, Aug. 14, 2020 (HealthDay News) — Excess mortality during the peak of the 1918 H1N1 influenza pandemic was comparable to that seen early in the COVID-19 pandemic outbreak in New York City, according to a research letter published online Aug. 13 in JAMA Network Open.
Convalescent Plasma Efficacious for Severe COVID-19
FRIDAY, Aug. 14, 2020 (HealthDay News) — Transfusion of convalescent plasma is efficacious in patients with severe COVID-19, according to a study published online Aug. 11 in The American Journal of Pathology.
Positivity Rates of SARS-CoV-2 Low for Children in England
Physical Therapist-Supervised Exercise Improves Outcomes After ACL Reconstruction 
Early Complications Common in Older Kidney Transplant Recipients 
PET/MRI Offers Diagnostic, Prognostic Value in Pediatric Epilepsy 
Less Intraoperative Crystalloid Fluid Not Tied to Worse Surgical Outcomes 
Socioeconomic Status Linked to Mortality After Acute Hip Fracture Surgery 
Relapse Rare After Appendiceal Adenocarcinoma Resection 
Disparities Identified in Home Health Care After Hip, Knee Replacement 
Preoperative IV Iron Beneficial for Patients With Anemia Undergoing Cardiac Surgery 
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