Here are what the editors at HealthDay consider to be the most important developments in Pathology for July 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 27 to 31, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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Plenty of COVID-19 Vaccine Coming, Fauci Says
FRIDAY, July 31, 2020 (HealthDay News) — When a COVID-19 vaccine is approved, there should be plenty of it available, Anthony Fauci, M.D., infectious diseases chief at the U.S. National Institutes of Health, told a House panel Friday, the Associated Press reported.
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Johns Hopkins University
COVID-19 Testing Needed Every Two Days to Reopen Colleges
FRIDAY, July 31, 2020 (HealthDay News) — Symptom-based screening alone is not sufficient to contain a COVID-19 outbreak on college campuses, according to a study published online July 31 in JAMA Network Open.
Global Epidemiology of COVID-19 Reported for Prepandemic Era
FRIDAY, July 31, 2020 (HealthDay News) — Many of the first COVID-19 cases reported from affected countries outside of mainland China involved recent travel to affected countries, according to a study published online July 29 in The Lancet Infectious Diseases.
Sex Differences in Income Vary With Proportion of Male Doctors
FRIDAY, July 31, 2020 (HealthDay News) — For surgical and nonsurgical specialists, sex differences in income vary with the proportion of male physicians in a practice, according to a study published online July 30 in The BMJ.
School Closures Linked to Decreased COVID-19 Incidence, Death
THURSDAY, July 30, 2020 (HealthDay News) — School closures in the United States were temporally associated with decreased COVID-19 incidence and mortality, according to a study published online July 29 in the Journal of the American Medical Association.
Young Children Have Higher Amounts of SARS-CoV-2 RNA
THURSDAY, July 30, 2020 (HealthDay News) — Young children with mild-to-moderate COVID-19 have higher amounts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA in their nasopharynx than older children and adults, according to a research letter published online July 30 in JAMA Pediatrics.
ACS Issues Updated Guideline for Cervical Cancer Screening
THURSDAY, July 30, 2020 (HealthDay News) — In a guideline update from the American Cancer Society, published online July 30 in CA: A Cancer Journal for Clinicians, recommendations are presented for cervical cancer screening of individuals at average risk.
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Most Gynecologic Cancer Therapy Not Tied to Higher COVID-19 Risk
THURSDAY, July 30, 2020 (HealthDay News) — For gynecologic oncology patients with COVID-19, the case fatality rate is 14.0 percent, and chemotherapy and recent major surgery do not predict COVID-19 severity or mortality, according to a study published online July 30 in Cancer.
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Depression, Anxiety May Be Signs That COVID-19 Is Attacking Brain
WEDNESDAY, July 29, 2020 (HealthDay News) — Depression and anxiety exhibited in COVID-19 patients may be a sign that the virus impacts the central nervous system, as these symptoms are closely associated with a loss of smell and taste rather than more severe manifestations of the virus, according to a study published online July 2 in The Laryngoscope.
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Burden of Pre-, Postmenopausal Breast Cancer Up Worldwide
TUESDAY, July 28, 2020 (HealthDay News) — There is evidence of an increasing burden of premenopausal and postmenopausal breast cancer worldwide, according to a study published in the August issue of The Lancet Global Health.
Myocardial Injury Seen in Many Early in Recovery From COVID-19
TUESDAY, July 28, 2020 (HealthDay News) — Many patients recently recovered from COVID-19 infection have cardiac involvement, according to a study published online July 27 in JAMA Cardiology.
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Indigenous American Ancestry Tied to HER2+ Breast Cancer
TUESDAY, July 28, 2020 (HealthDay News) — Indigenous American (IA) origin could partly contribute to the higher incidence of human epidermal growth factor receptor 2-positive (HER2+) breast cancer in Latinas, according to a study recently published in Cancer Research.
Postmarketing Surveillance Helps Identify Vaccine Safety Issues
TUESDAY, July 28, 2020 (HealthDay News) — A review of all safety-related labeling changes for FDA-approved vaccines during a 20-year period shows vaccines are largely safe, and many of the safety issues are identified through postmarketing surveillance, according to a study published online July 28 in the Annals of Internal Medicine.
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COVID-19 Vaccine Candidate Now in Final Phase Testing
MONDAY, July 27, 2020 (HealthDay News) — A vaccine developed by the U.S. National Institutes of Health and Moderna has entered the final phase of testing, the Associated Press reported Monday.
Large Proportion of COVID-19 Studies Have Low-Level Evidence
MONDAY, July 27, 2020 (HealthDay News) — A large proportion of studies on COVID-19 have a low level of evidence, according to a research letter published online July 27 in JAMA Internal Medicine.
Higher Prepregnancy Serum Creatinine Linked to Preterm Birth
MONDAY, July 27, 2020 (HealthDay News) — Increased levels of prepregnancy serum creatinine are associated with an increased risk for preterm birth, according to a study published in the July 27 issue of CMAJ, the journal of the Canadian Medical Association.
Metabolomics Screening Tool May Detect Autism Spectrum Disorder
MONDAY, July 27, 2020 (HealthDay News) — A metabolomics screening tool may detect more than 50 percent of individuals with autism spectrum disorder (ASD), according to a study published online June 18 in Autism Research.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 20 to 24, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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Midnasal Swab Done by Patient at Home Detects SARS-CoV-2
FRIDAY, July 24, 2020 (HealthDay News) — For detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in symptomatic patients, unsupervised home midnasal swab collection is comparable to clinician-collected nasopharyngeal swab collection, according to a research letter published online July 22 in JAMA Network Open.
CDC Guidance Issued for Testing, Management of HCP Exposed to Hep C
FRIDAY, July 24, 2020 (HealthDay News) — In a U.S. Centers for Disease Control and Prevention guidance report, published in the July 24 issue of Morbidity and Mortality Weekly Report, recommendations are presented for testing and clinical management of health care personnel (HCP) exposed to the hepatitis C virus (HCV).
Chimpanzee Adenovirus-Vectored Vaccine Promising for COVID-19
FRIDAY, July 24, 2020 (HealthDay News) — A chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein has acceptable safety and induces antibody and T-cell immune responses, according to a study published online July 20 in The Lancet.
Financial Health of Hospitals ‘Dire’ Due to COVID-19
THURSDAY, July 23, 2020 (HealthDay News) — COVID-19 continues to cause financial peril for U.S. hospitals, according to a report released by the American Hospital Association (AHA).
New Guidelines Released for Recovering COVID-19 Patients to Leave Isolation
THURSDAY, July 23, 2020 (HealthDay News) — Many recovering COVID-19 patients in the United States will now be able to leave isolation without further testing to show they are virus-free, the U.S. Centers for Disease Control and Prevention said Wednesday.
Most Individuals in U.S. Have Not Been Infected With SARS-CoV-2
THURSDAY, July 23, 2020 (HealthDay News) — During March to early May 2020, most individuals in the United States had not been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), although the estimated number of infections seems to have been much higher than the number of reported cases, according to a study published online July 21 in JAMA Internal Medicine.
Ad5-Vectored COVID-19 Vaccine Immunogenic in Healthy Adults
THURSDAY, July 23, 2020 (HealthDay News) — The nonreplicating adenovirus type-5 (Ad5)-vectored COVID-19 vaccine appears safe and induces immune responses at a dose of 5×1010 viral particles, according to a study published online July 20 in The Lancet.
No Spike Seen in Cases of Polio-Like Condition in Children
WEDNESDAY, July 22, 2020 (HealthDay News) — It is not clear if acute flaccid myelitis (AFM) will follow its usual pattern and if we will see a spike of cases in 2020, the U.S. Centers for Disease Control and Prevention says.
Routine Hepatitis C Testing at FQHCs Would Be Cost-Effective
WEDNESDAY, July 22, 2020 (HealthDay News) — Routine hepatitis C virus (HCV) testing at federally qualified health centers (FQHCs) would be cost-effective and could improve outcomes for people with HCV infections, according to a study published online June 27 in The American Journal of Medicine.
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Predictors of Amyloid-β Deposits Identified in Oldest Old
WEDNESDAY, July 22, 2020 (HealthDay News) — Predictors of amyloid-β (Aβ) deposition have been identified in the oldest old, according to a study published online July 22 in Neurology.
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Epidemiology of Herpes Simplex Virus in Europe Transitioning
WEDNESDAY, July 22, 2020 (HealthDay News) — The epidemiology of herpes simplex virus (HSV)-1 is transitioning away from oral acquisition in childhood with an increasing proportion of HSV-1 detection in genital herpes, according to a study published online July 16 in BMJ Global Health.
11.8 Percent of Household Contacts of Index Patients Have COVID-19
TUESDAY, July 21, 2020 (HealthDay News) — Overall, 11.8 percent of household contacts of index COVID-19 patients in South Korea have COVID-19 compared with 1.9 percent of nonhousehold contacts, according to a study published online July 16 in Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention.
Assessing Symptoms, Blood, Stool Markers Best for Identifying Pediatric IBD
TUESDAY, July 21, 2020 (HealthDay News) — For pediatric patients with nonbloody diarrhea, evaluating symptoms plus blood and stool markers is the optimal test strategy for predicting inflammatory bowel disease (IBD), according to a study published online July 21 in Pediatrics.
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Blood Test Can Detect Cancer Before Conventional Diagnosis
TUESDAY, July 21, 2020 (HealthDay News) — A noninvasive blood test based on circulating tumor DNA methylation can detect cancer four years before conventional diagnosis, according to a study published online July 21 in Nature Communications.
Blood Type Not Linked to Progression to Severe COVID-19
TUESDAY, July 21, 2020 (HealthDay News) — For COVID-19 patients, blood type is not associated with the risk for progression to severe disease, according to a study published online July 12 in the Annals of Hematology.
Pooled Sampling Approved for COVID-19 Test
MONDAY, July 20, 2020 (HealthDay News) — An emergency use authorization (EUA) has been issued for the Quest Diagnostics Quest SARS-CoV-2 real-time reverse transcription polymerase chain reaction test for use with pooled samples containing up to four individual swab specimens collected under observation, the U.S. Food and Drug Administration said Saturday.
Surgical Delay Worsens Survival for Some Gastrointestinal Cancers
MONDAY, July 20, 2020 (HealthDay News) — Surgical delay is associated with an increased risk in some gastrointestinal malignancies, and understanding the impact on outcomes may assist surgeons in triaging patients whose surgeries were delayed due to the COVID-19 pandemic, according to research published online June 30 in the Journal of Gastrointestinal Surgery.
Reducing Testing Delay Crucial for Slowing COVID-19 Transmission
MONDAY, July 20, 2020 (HealthDay News) — Minimizing testing delay has the largest impact on reducing onward transmission of COVID-19, according to a study published online July 16 in The Lancet Public Health.
Reminder + FIT Test Cost-Effective for Promoting CRC Screening
Physical Therapist-Supervised Exercise Improves Outcomes After ACL Reconstruction 
Early Complications Common in Older Kidney Transplant Recipients 
PET/MRI Offers Diagnostic, Prognostic Value in Pediatric Epilepsy 
Less Intraoperative Crystalloid Fluid Not Tied to Worse Surgical Outcomes 
Socioeconomic Status Linked to Mortality After Acute Hip Fracture Surgery 
Relapse Rare After Appendiceal Adenocarcinoma Resection 
Disparities Identified in Home Health Care After Hip, Knee Replacement 
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