Here are what the editors at HealthDay consider to be the most important developments in Pathology for June 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Brain Iron Concentrations Increased in Alzheimer Disease
TUESDAY, June 30, 2020 (HealthDay News) — Patients with Alzheimer disease (AD) have increased iron concentration in the deep gray matter and neocortical regions compared with healthy controls (HC), according to a study published online June 30 in Radiology.
ID, Isolation of SARS-CoV-2 Vital in Correctional Facilities
TUESDAY, June 30, 2020 (HealthDay News) — Prompt identification and isolation of individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is important for reducing transmission in correctional and detention facilities, according to research published in the June 29 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
U.S. Could See 100,000 New Cases of COVID-19 Each Day, Fauci Says
TUESDAY, June 30, 2020 (HealthDay News) — Top U.S. infectious disease expert Anthony Fauci, M.D., warned Congress on Tuesday that COVID-19 infections could climb to 100,000 new cases daily unless ongoing outbreaks are contained.
FBI Warns of Scammers Selling Fake COVID-19 Antibody Tests
TUESDAY, June 30, 2020 (HealthDay News) — Fake or unapproved COVID-19 antibody tests are being sold by scammers, the Federal Bureau of Investigation warns.
Global Burden of Thyroid Cancer Is Increasing
TUESDAY, June 30, 2020 (HealthDay News) — There is an increasing global burden of thyroid cancer, according to a study published online June 26 in JAMA Network Open.
Antibody Tests ID COVID-19 Two to Three Weeks After Symptoms
MONDAY, June 29, 2020 (HealthDay News) — Antibody testing may detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, with sensitivity peaking at three weeks since symptom onset, according to a review published online June 25 in the Cochrane Library.
CDC: U.S. COVID-19 Rates Much Higher Than Reported
MONDAY, June 29, 2020 (HealthDay News) — Actual COVID-19 infection rates in many areas of the United States are more than 10 times higher than reported rates, a U.S. Centers for Disease Control and Prevention study suggests.
The New York Times Article
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Trump Administration Asks Supreme Court to Overturn Affordable Care Act
FRIDAY, June 26, 2020 (HealthDay News) — The Trump administration has asked the Supreme Court to overturn the Affordable Care Act (ACA).
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 22 to 26, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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U.S. Has Second Day of Record Rise in COVID-19 Cases; Young People Fueling Trend
FRIDAY, June 26, 2020 (HealthDay News) — As the United States reported yet another record-breaking number of COVID-19 cases on Thursday, public health officials warned that younger Americans now account for an ever-growing percentage of infections.
Genomewide Level Associations Identified for Severe COVID-19
FRIDAY, June 26, 2020 (HealthDay News) — Patients with COVID-19 and severe disease have associations at locus 3p21.31 and 9q34.2, which are significant at the genomewide level, according to a study published online June 17 in the New England Journal of Medicine.
Women Have More Brain Changes Related to Alzheimer Disease
FRIDAY, June 26, 2020 (HealthDay News) — Cognitively normal women have increased Alzheimer disease endophenotype, with higher β-amyloid deposition, lower glucose metabolism, and lower gray and white matter volumes, according to a study published online June 24 in Neurology.
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Congo Marks End of World’s Second Deadliest Ebola Outbreak
THURSDAY, June 25, 2020 (HealthDay News) — The end of the second deadliest Ebola outbreak in history was officially marked Thursday by the Democratic Republic of Congo.
Texas Pauses Reopening as COVID-19 Cases Rise
THURSDAY, June 25, 2020 (HealthDay News) — As COVID-19 cases surge in Texas, the state is pausing its reopening process and freeing up hospital beds for COVID-19 patients.
Model May Help Predict Risk for Testing Positive for COVID-19
THURSDAY, June 25, 2020 (HealthDay News) — It is possible to predict the likelihood of testing positive for COVID-19, according to a study published online June 10 in CHEST.
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Inhibition of Sclerostin May Increase Cardiovascular Risk
THURSDAY, June 25, 2020 (HealthDay News) — Inhibition of sclerostin with romosozumab may increase cardiovascular risk, according to research published in the June 24 issue of Science Translational Medicine.
U.S. Burden of Skin and Subcutaneous Diseases Increasing
THURSDAY, June 25, 2020 (HealthDay News) — The U.S. burden of skin and subcutaneous diseases is large but varies geographically, according to a study published online June 10 in JAMA Dermatology.
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Sanofi Speeds COVID-19 Vaccine Efforts
WEDNESDAY, June 24, 2020 (HealthDay News) — French drugmaker Sanofi has shortened its timeline to get a COVID-19 vaccine on the market.
J&J Ordered to Pay $2.1 Billion in Talcum Product Lawsuit
WEDNESDAY, June 24, 2020 (HealthDay News) — Johnson & Johnson and a subsidiary must pay $2.1 billion in damages to women who said their ovarian cancers were caused by the company’s baby powder and other talcum products, a Missouri appeals court ruled Tuesday.
Bayer to Pay $10 Billion to Settle Roundup Lawsuits
WEDNESDAY, June 24, 2020 (HealthDay News) — Bayer has agreed to pay more than $10 billion to settle thousands of U.S. lawsuits alleging that its weedkiller Roundup causes cancer.
Odds of Pregnancy Decrease With Prolonged Embryo Storage
WEDNESDAY, June 24, 2020 (HealthDay News) — Prolonged storage of embryos after vitrification is associated with a reduced likelihood of biochemical pregnancy, clinical pregnancy, and live birth, according to a study published online June 23 in Human Reproduction.
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Patients With COVID-19 Mount Acute Cortisol Stress Response
WEDNESDAY, June 24, 2020 (HealthDay News) — Patients with COVID-19 mount a marked and appropriate acute cortisol stress response, according to a research letter published online June 19 in The Lancet Diabetes & Endocrinology.
Tocilizumab Shows Promise for Treatment of COVID-19
WEDNESDAY, June 24, 2020 (HealthDay News) — Use of tocilizumab to target cytokine release syndrome (CRS) seems beneficial for patients with COVID-19, according to a study published online June 15 in CHEST.
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Subtypes, Genetic Links Identified for Polycystic Ovary Syndrome
TUESDAY, June 23, 2020 (HealthDay News) — Distinct subtypes of polycystic ovary syndrome (PCOS) with novel genetic associations have been identified, according to a study published online June 23 in PLOS Medicine.
COVID-19 Vaccine May Be Available by Late 2020, Early 2021: Fauci
TUESDAY, June 23, 2020 (HealthDay News) — There could be a COVID-19 vaccine by the end of this year or early next year, according to Anthony Fauci, M.D., infectious diseases chief at the U.S. National Institutes of Health.
African-American Participation Inadequate in Cancer Drug Trials
TUESDAY, June 23, 2020 (HealthDay News) — African-Americans are underrepresented in clinical trials leading to approval of cancer medications, according to a research letter published online June 23 in the Annals of Internal Medicine.
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Transmissibility of SARS-CoV-2 High Within Households
MONDAY, June 22, 2020 (HealthDay News) — Severe acute respiratory syndrome coronavirus 2 has high transmissibility within households, according to a study published online June 17 in The Lancet Infectious Diseases.
Adult T2DM Susceptibility May Be Identifiable in Children
MONDAY, June 22, 2020 (HealthDay News) — Metabolic traits associated with adult diabetes risk may be detectable by age 8 years, according to a study published online June 19 in Diabetes Care.
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 15 to 19, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
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Early Data Show No Protest-Related Increases in COVID-19 Infections
FRIDAY, June 19, 2020 (HealthDay News) — Antiracism protests in the United States have not led to increases in new cases of the coronavirus that causes COVID-19, early data show.
The Wall Street Journal Article
Scientists Say Journal Should Retract Mask Study
FRIDAY, June 19, 2020 (HealthDay News) — A study on the use of masks to protect against the new coronavirus should be retracted by the Proceedings of the National Academy of Sciences because it contains “egregious errors” and “verifiably false” statements, a group of scientists say in a letter to the journal’s editors.
Isolation, Contact Tracing Combo Can Cut COVID-19 Transmission
FRIDAY, June 19, 2020 (HealthDay News) — Combined isolation and tracing strategies can reduce COVID-19 transmission more than mass testing or self-isolation alone, according to a study published online June 16 in The Lancet Infectious Diseases.
Nine Texas Mayors Ask Governor for Power to Mandate Face Masks
THURSDAY, June 18, 2020 (HealthDay News) — Mayors in Houston, Dallas, Austin, San Antonio, and five other Texas municipalities want Gov. Greg Abbott to give them the power to require people to wear masks in public “where physical distancing cannot be practiced.”
Sociodemographic Gaps Found in COVID-19 Incidence, Knowledge
THURSDAY, June 18, 2020 (HealthDay News) — There are sociodemographic gaps in the reported incidence of COVID-19 and knowledge regarding its spread and symptoms, according to a study published online June 18 in JAMA Network Open.
Face-Mask Use May Mitigate Spread of COVID-19
THURSDAY, June 18, 2020 (HealthDay News) — Requiring face-mask use in public may help to mitigate the spread of COVID-19, according to a report published online June 16 in Health Affairs.
Clinical, Epidemiological Features of Pediatric SARS-CoV-2 ID’d
THURSDAY, June 18, 2020 (HealthDay News) — Clinical and epidemiological characteristics of pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are described in an article published online June 16 in PLOS Medicine.
Record-High Spikes in COVID-19 Cases Seen in Arizona, Florida, Texas
WEDNESDAY, June 17, 2020 (HealthDay News) — After reopening, states such as Arizona, Florida, and Texas are all seeing record-high one-day increases in COVID-19 cases.
U.S. Insurers Should Not Charge Copays for COVID-19 Vaccine
WEDNESDAY, June 17, 2020 (HealthDay News) — Health insurance companies are expected to cover vaccines for the new coronavirus without charging copays, U.S. officials say.
Mild Thyroid Dysfunction Common in Women With Subfertility
WEDNESDAY, June 17, 2020 (HealthDay News) — Among women with a history of miscarriage or subfertility trying for a pregnancy, mild subclinical hypothyroidism (SCH) is common, according to a study published online June 17 in the Journal of Clinical Endocrinology & Metabolism.
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Risk for COVID-19 Reinfection Remains Unknown
WEDNESDAY, June 17, 2020 (HealthDay News) — The potential risk for reinfection with COVID-19 remains a concern, but evidence is scarce, according to Jeffrey Shaman, Ph.D., director of the climate and health program at Columbia University, who recently spoke with HD Live! about his research and the risk for reinfection with COVID-19.
CDC: Cumulative Incidence of COVID-19 403.6 Per 100,000 in U.S.
TUESDAY, June 16, 2020 (HealthDay News) — The cumulative incidence of COVID-19 is 403.6 cases per 100,000 persons in the United States, and hospitalization and death rates are six and 12 times higher, respectively, for those with underlying conditions, according to research published in the June 15 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
Self-Collected Nasal Swabs Acceptable for SARS-CoV-2 Testing
TUESDAY, June 16, 2020 (HealthDay News) — Patient-collected lower nasal specimens may be acceptable for severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) testing, according to a research letter published online June 12 in JAMA Network Open.
Face Masks Most Effective Means to Avert COVID-19 Transmission
TUESDAY, June 16, 2020 (HealthDay News) — Mandated face coverings represent the most effective means to prevent interhuman transmission of COVID-19, according to a study published online June 11 in the Proceedings of the National Academy of Sciences.
Physical Therapist-Supervised Exercise Improves Outcomes After ACL Reconstruction
Early Complications Common in Older Kidney Transplant Recipients
PET/MRI Offers Diagnostic, Prognostic Value in Pediatric Epilepsy
Less Intraoperative Crystalloid Fluid Not Tied to Worse Surgical Outcomes
Socioeconomic Status Linked to Mortality After Acute Hip Fracture Surgery
Relapse Rare After Appendiceal Adenocarcinoma Resection
Disparities Identified in Home Health Care After Hip, Knee Replacement
Preoperative IV Iron Beneficial for Patients With Anemia Undergoing Cardiac Surgery