November 2018 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for November 2018. This roundup includes the latest research news from journal articles, as […]

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for November 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Family Functioning Does Not Impact Family Dinner, Diet Link

FRIDAY, Nov. 30, 2018 (HealthDay News) — Among adolescents and young adults, family dinner frequency is associated with healthful dietary intake, regardless of family functioning, according to a study published online Nov. 21 in JAMA Network Open.

Abstract/Full Text

Limiting Social Media May Improve Psychological Well-Being

FRIDAY, Nov. 30, 2018 (HealthDay News) — Limiting social media use to 30 minutes per day may lead to significant improvement in well-being, according to a study published in the December issue of the Journal of Social and Clinical Psychology.

Abstract/Full Text

Case Description Can Reliably Define Acute Flaccid Myelitis

FRIDAY, Nov. 30, 2018 (HealthDay News) — A case description can reliably define patients with acute flaccid myelitis (AFM), according to a study published online Nov. 30 in JAMA Pediatrics.

Abstract/Full Text
Editorial 1
Editorial 2

For Teen Girls, Depression May Predict Subsequent Alcohol Use

FRIDAY, Nov. 30, 2018 (HealthDay News) — For adolescent girls, depression, but not anxiety, predicts future alcohol use, according to a study published online Nov. 25 in Alcoholism: Clinical and Experimental Research.

Abstract/Full Text (subscription or payment may be required)

Results of Pediatric Genomic Epilepsy Tests Often Reclassified

FRIDAY, Nov. 30, 2018 (HealthDay News) — The interpretation of genomic epilepsy tests has evolved rapidly in the last five years, and genetic variants identified in pediatric patients are often reclassified, according to research published online Nov. 5 in JAMA Pediatrics.

Abstract/Full Text (subscription or payment may be required)

Most Bills Enacted Into Law Limit Vaccine Exemptions

THURSDAY, Nov. 29, 2018 (HealthDay News) — Most proposed bills in state legislatures from 2011 to 2017 sought to expand access to immunization exemptions, but the majority of bills enacted into law limited exemptions, according to a study published online Nov. 29 in the American Journal of Public Health.

Abstract/Full Text (subscription or payment may be required)

Climate Change Ups Heat Deaths, Especially Among Elderly

THURSDAY, Nov. 29, 2018 (HealthDay News) — Risk for heat-related disease and death is rising worldwide due to climate change, according to a report published online Nov. 28 in The Lancet.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Liquid Biopsy Can Assess Tx Response of Peds Brain Tumors

THURSDAY, Nov. 29, 2018 (HealthDay News) — A liquid biopsy using blood or cerebrospinal fluid (CSF) can effectively quantify changes in mutation levels among pediatric patients being treated for diffuse midline gliomas (DMGs), according to a study recently published in Clinical Cancer Research.

Abstract/Full Text (subscription or payment may be required)

ADHD Diagnosis, Treatment Up for August-Born Children

WEDNESDAY, Nov. 28, 2018 (HealthDay News) — In states with a Sept. 1 cutoff for kindergarten entry, the rates of attention-deficit/hyperactivity disorder (ADHD) diagnosis and treatment are higher for children born in August than those born in September, according to a study published in the Nov. 29 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Feature Tagging of Home Videos Promising in Autism Diagnosis

WEDNESDAY, Nov. 28, 2018 (HealthDay News) — Feature tagging of home videos for machine learning classification of autism spectrum disorder (ASD) with the use of a mobile device produces accurate results in short time frames, according to a study published online Nov. 27 in PLOS Medicine.

Abstract/Full Text

Large at Birth, Maternal Diabetes Up Child’s Risk for Obesity

WEDNESDAY, Nov. 28, 2018 (HealthDay News) — Large for gestational age (LGA) is a stronger marker than maternal diabetes for subsequently being overweight or obese in early childhood, according to a study published online Nov. 13 in Diabetologia.

Abstract/Full Text (subscription or payment may be required)

Amblyopia Linked to Lower Self-Perception in Children

WEDNESDAY, Nov. 28, 2018 (HealthDay News) — Children with amblyopia report lower self-perception for scholastic, social, and athletic measures, which may be associated with slower reading speed and worse motor skills, according to a study published online Nov. 15 in JAMA Ophthalmology.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required

USPSTF: Evidence Lacking for Prevention of Child Maltreatment

TUESDAY, Nov. 27, 2018 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) concludes that the evidence on the benefits and harms of primary care interventions for preventing child maltreatment is currently inadequate. These findings form the basis of a final recommendation statement published online Nov. 27 in the Journal of the American Medical Association.

Final Recommendation Statement
Evidence Report
Editorial (subscription or payment may be required)

FDA to Update Medical Device Approvals Process

TUESDAY, Nov. 27, 2018 (HealthDay News) — A major update of the United States’ system for approving medical devices was announced yesterday by the Food and Drug Administration.

CBS/AP News Article
More Information

FDA: Safe to Eat Romaine Lettuce Again, but Check Labels

TUESDAY, Nov. 27, 2018 (HealthDay News) — In a statement released late yesterday, the U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D., announced that the agency was lifting its advisory against eating romaine lettuce, first put in place last Tuesday. At that point, the agency had not been able to narrow down the source of the tainted lettuce. But now the source seems to be “end-of-season” lettuce harvested somewhere in the Central Coast regions of central and northern California. And “harvesting of romaine lettuce from this region has [already] ended for the year,” Gottlieb noted.

More Information: FDA
More Information: CDC

Prevalence of Eating Disorders 1.4 Percent in Preteens

TUESDAY, Nov. 27, 2018 (HealthDay News) — The prevalence of eating disorders among 9- to 10-year-olds in the United States is 1.4 percent, with no difference in prevalence between boys and girls, according to a research letter published online Nov. 26 in JAMA Pediatrics.

Abstract/Full Text (subscription or payment may be required)

Four Principles Underlie Patient and Family Partnership in Care

TUESDAY, Nov. 27, 2018 (HealthDay News) — Patient and family partnership in care should include treatment of patients and families with dignity and respect, their active engagement in all aspects of care, and their contribution to the improvement of health care systems and education of health care professionals, according to a position paper published online Nov. 27 in the Annals of Internal Medicine.

Position Paper
Editorial (subscription or payment may be required)

Less Pediatric Screen Time Tied to Better Well-Being

TUESDAY, Nov. 27, 2018 (HealthDay News) — A higher amount of screen time per day is associated with decreased psychological well-being in children and adolescents, according to a study published in the December issue of Preventive Medicine Reports.

Abstract/Full Text

Early Antibiotic Use May Be Tied to Higher Childhood Body Weight

MONDAY, Nov. 26, 2018 (HealthDay News) — Antibiotic use in children <24 months of age is associated with a slightly higher body weight at 5 years of age, according to a study published recently in Pediatrics.

Abstract/Full Text (subscription or payment may be required)

Newborns Infected With Ebola in Congo Outbreak

MONDAY, Nov. 26, 2018 (HealthDay News) — Ebola infections in newborns are being reported in the current outbreak of the deadly disease in Congo, the World Health Organization says.

AP News Article
More Information: CDC

Estimated 2.5 Percent of U.S. Children Diagnosed With Autism

MONDAY, Nov. 26, 2018 (HealthDay News) — The prevalence of parent-reported autism spectrum disorder (ASD) is estimated at 2.5 percent among U.S. children aged 3 to 17 years, according to a study published online Nov. 26 in Pediatrics.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

ACA Coverage Substantial, but Did Not Impact Labor Markets

MONDAY, Nov. 26, 2018 (HealthDay News) — Millions of workers gained insurance coverage under the Affordable Care Act (ACA) without adverse effects on labor markets, according to a report published by the Robert Wood Johnson Foundation and the Urban Institute.

Report: How Have Workers Fared Under the ACA?

Child Overweight, Obesity Linked to Increased Asthma Risk

MONDAY, Nov. 26, 2018 (HealthDay News) — Children who are overweight or obese have an increased risk for asthma, according to a study published online Nov. 26 in Pediatrics.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Probiotics Show No Benefits for Pediatric Acute Gastroenteritis

MONDAY, Nov. 26, 2018 (HealthDay News) — For children with acute gastroenteritis, probiotics show no significant benefit versus placebo, according to two studies published in the Nov. 22 issue of the New England Journal of Medicine.

Abstract/Full Text – Schnadower (subscription or payment may be required)
Abstract/Full Text – Freedman (subscription or payment may be required)
Editorial (subscription or payment may be required)

Youth Smoking Decline Mirrors Rise in Vaping Popularity

MONDAY, Nov. 26, 2018 (HealthDay News) — Even with the rapid rise in popularity of electronic cigarettes, there has been a simultaneous decline in smoking prevalence among U.S. teens and young adults, suggesting e-cigarettes may not prompt young people to start smoking, according to a study published online Nov. 20 in Tobacco Control.

Abstract/Full Text

FDA Approves Drug to Treat Rare Immune Disease

WEDNESDAY, Nov. 21, 2018 (HealthDay News) — The U.S. Food and Drug Administration on Monday approved Gamifant (emapalumab-lzsg) for the treatment of primary hemophagocytic lymphohistiocytosis (HLH) in pediatric (as young as newborn) and adult patients who have refractory, recurrent, or progressive disease or intolerance with conventional HLH treatment.

More Information

U of Maryland Student Dies of Adenovirus-Related Illness

WEDNESDAY, Nov. 21, 2018 (HealthDay News) — An 18-year-old University of Maryland student has died from an adenovirus-related illness, and there have been reports of five other cases among students.

CBS News Article
More Information: CDC

Few Mandatory Pediatric Postmarketing Studies Completed

WEDNESDAY, Nov. 21, 2018 (HealthDay News) — During a median follow-up of 6.8 years, only 33.8 percent of mandatory pediatric postmarketing studies were completed, according to a study published online Nov. 19 in JAMA Pediatrics.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

ED Utilization Up for Pediatric mTBI After TBI Legislation

WEDNESDAY, Nov. 21, 2018 (HealthDay News) — Implementation of state youth traumatic brain injury (TBI) legislation correlated with an increase in pediatric emergency department utilization for youth sports- and recreation-related mild TBI (mTBI) evaluation, according to a study published in the November/December issue of the Journal of Head Trauma Rehabilitation.

Abstract/Full Text (subscription or payment may be required)

CDC Announces Acute Flaccid Myelitis Task Force

TUESDAY, Nov. 20, 2018 (HealthDay News) — A task force to investigate a rising number of cases of a rare polio-like disease among children in the United States has been created by the U.S. Centers for Disease Control and Prevention.

More Information

FDA: Another E. coli Outbreak Linked to Romaine Lettuce

TUESDAY, Nov. 20, 2018 (HealthDay News) — The U.S. Food and Drug Administration and U.S. Centers for Disease Control and Prevention along with health officials from various states are asking American consumers to avoid romaine lettuce due to an outbreak of Escherichia coli illness.

FDA Fast Facts
CDC Food Safety Alert

Vaccine-Exempt Students Behind N.C. Chickenpox Outbreak

TUESDAY, Nov. 20, 2018 (HealthDay News) — North Carolina’s largest chickenpox outbreak in decades is centered in a primary school with a large number of vaccine-exempt students, according to health officials.

BBC News Article

Prenatal Nitric Oxide Exposure Linked to Higher Risk for Autism

TUESDAY, Nov. 20, 2018 (HealthDay News) — Prenatal exposure to nitric oxide (NO) is associated with an increased risk for autism spectrum disorder (ASD), according to a study published online Nov. 19 in JAMA Pediatrics.

Abstract/Full Text (subscription or payment may be required)

11th Child Dies in Adenovirus Outbreak at N.J. Care Facility

MONDAY, Nov. 19, 2018 (HealthDay News) — An 11th child has died in an outbreak of a respiratory virus at the Wanaque Center for Nursing and Rehabilitation in New Jersey, health officials say.

CBS News Article
More Information: CDC

Cap’n Crunch Cereal Recalled Due to Salmonella Scare

MONDAY, Nov. 19, 2018 (HealthDay News) — A small number of boxes of Cap’n Crunch’s Peanut Butter Crunch are being recalled due to potential Salmonella contamination, Quaker Oats says.

FDA Recall Notice
More Information: CDC

FDA Warns Against Giving Honey-Filled Pacifiers to Infants

MONDAY, Nov. 19, 2018 (HealthDay News) — Pacifiers filled with or dipped in honey should not be given to infants, the U.S. Food and Drug Administration says.

More Information

Prevalence of Food Allergy 7.6 Percent in U.S. Children

MONDAY, Nov. 19, 2018 (HealthDay News) — The prevalence of food allergy (FA) is 7.6 percent among children in the United States, according to a study published online Nov. 19 in Pediatrics.

Abstract/Full Text

CDC: Increase Seen in Salmonella Illnesses From Ground Beef

FRIDAY, Nov. 16, 2018 (HealthDay News) — There have been 126 more cases of illness added to an investigation into a Salmonella outbreak linked to recalled ground beef products from JBS Tolleson Inc., bringing the total to 246 cases in 25 states, the U.S. Centers for Disease Control and Prevention says.

CDC Food Safety Alert

AAP Updates Management of Sport-Related Concussion

FRIDAY, Nov. 14, 2018 (HealthDay News) — Recommendations have been developed for the diagnosis and management of pediatric sport-related concussion (SRC), according to a clinical report published online Nov. 12 in Pediatrics.

Abstract/Full Text

Epinephrine Personal Autoinjectors Cost-Effective at $24

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