Latest Cystic Fibrosis news
Drug Combo Tolerated in Younger Children With Cystic Fibrosis
by modernClinician Editorial Team
Lumacaftor/ivacaftor treatment is generally safe and well tolerated for children aged 2 to 5 years with cystic fibrosis homozygous for the F508del-CFTR mutation, according to a study published online Jan. 24 in The Lancet Respiratory Medicine.
Triple Combo Regimens May Address Cause of Cystic Fibrosis
by modernClinician Editorial Team
Triple therapy with VX-659 or VX-445 combined with tezacaftor-ivacaftor shows promise for the treatment of adult patients with cystic fibrosis who have mutations in the cystic fibrosis transmembrane conductance regulator, according to two studies published online Oct. 18 in the New England Journal of Medicine. The studies were published to coincide with presentation at the annual North American Cystic Fibrosis Conference, held from Oct. 18 to 20 in Denver.
Azithromycin Cuts Pulmonary Exacerbation in CF With Early Pa
by modernClinician Editorial Team
For children with cystic fibrosis and early Pseudomonas aeruginosa infection, the risk of pulmonary exacerbation is significantly reduced with the addition of azithromycin to tobramycin inhalation solution, according to a study published online June 11 in the American Journal of Respiratory and Critical Care Medicine.
Respiratory Microbiome May Influence Inflammation in CF
by modernClinician Editorial Team
Reduced bacterial diversity in the upper and lower airways in infants with cystic fibrosis is associated with use of prophylactic antibiotics and younger age at sampling, while less diversity in lavage samples is associated with lower inflammation, according to a study published online July 14 in the Annals of the American Thoracic Society.
Healthy Lifestyle in Early Childhood Linked to Lower Risk for IBD 
Adults Hold Outdated Beliefs About Antibiotics 
NEWS2 Scores Can ID Patients With Suspected Sepsis Needing Timely Treatment 
CHEST Issues Guidelines for Management of Adult Bronchiectasis Related Articles
Guidelines Developed to Improve Newborn Screening for Cystic Fibrosis 
Challenged Urine Bicarbonate Excretion Tied to CFTR Function in Cystic Fibrosis 
Newborn Screening for Cystic Fibrosis Less Accurate in Minorities 
Racial, Ethnic-Minority Infants Older at First Cystic Fibrosis Evaluation Monthly Specialist Briefings
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