Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for December 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
New Guidelines Address Care for Malignant Pleural Effusions
FRIDAY, Dec. 28, 2018 (HealthDay News) — New clinical practice guidelines for the management of malignant pleural effusions were published in the January issue of the Annals of the American Thoracic Society.
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Second-Line Antidiabetic Meds May Impact Cardiovascular Risk
FRIDAY, Dec. 28, 2018 (HealthDay News) — For adults with type 2 diabetes initiating second-line antidiabetic medications (ADM), cardiovascular risk is increased with use of sulfonylureas or basal insulin versus newer ADM classes, according to a study published online Dec. 21 in JAMA Network Open.
ACOG Updates Guidelines for Gestational HTN, Preeclampsia
FRIDAY, Dec. 28, 2018 (HealthDay News) — The American College of Obstetricians & Gynecologists (ACOG) has updated its guidance on the management of gestational hypertension and preeclampsia as well as chronic hypertension in pregnant women; the two practice bulletins were published in the January issue of Obstetrics & Gynecology.
Gestational Hypertension and Preeclampsia
Chronic Hypertension in Pregnancy
Effect Sizes Uncertain for Meds Versus Placebo in Knee OA
FRIDAY, Dec. 28, 2018 (HealthDay News) — For patients with knee osteoarthritis and at least 12 months of follow-up, there is uncertainty around estimates of effect size for the change in pain in association with medications versus placebo, according to a meta-analysis published in the Dec. 25 issue of the Journal of the American Medical Association.
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Review Highlights Lack of Tx Options for Prurigo Nodularis
FRIDAY, Dec. 28, 2018 (HealthDay News) — A new review, published in the Journal of the American Academy of Dermatology, provides evidence-based guidance for practitioners treating the dermatologic condition prurigo nodularis and highlights gaps in treatment development and research.
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Low-Priced Generic Drugs Most Likely to Have Shortages
THURSDAY, Dec. 27, 2018 (HealthDay News) — The lowest-priced generic drugs are more likely to experience shortages, according to a study published in the November issue of Value in Health.
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More Than Two-Thirds of Drug OD Deaths in 2017 Involved Opioids
Homicide, Suicide, and Overdose Leading Causes of Maternal Death 
Model Predicts Poor Outcomes Within 30 Days of a Before Medically Advised Discharge 
Fewer Than Half of Drug Overdose Survivors Go to the Hospital 
2000 to 2023 Saw Rise in Pediatric Exposure to Medications, Supplements 
Long-Term Medication Adherence Tied to Lower Cardiovascular Event Rate in Type 2 Diabetes .jpg)
Warning Symptoms, Clinical History Can Predict Sudden Cardiac Arrest 
Protocol IDs Patients Who Can Be Treated While Seated in the ED .jpg)
Once-Weekly Oral Islatravir-Lenacapavir Noninferior to Daily B/F/TAF in HIV 
