June 2020 Briefing – Pathology

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Many of the Initial COVID-19 Treatment Trials Poorly Designed

FRIDAY, June 12, 2020 (HealthDay News) — Many clinical trials for COVID-19 treatments are limited by their design, with one-third excluding clinical end points, according to research published online June 9 in BMJ Open.

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Exclusive Breastfeeding May Prevent Weight Gain in At-Risk Children

FRIDAY, June 12, 2020 (HealthDay News) — Exclusive breastfeeding to 5 months can attenuate the impact of genetic risk on body mass index (BMI) increase during childhood, according to a study published online June 11 in PLOS Genetics.

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Face-Mask Use by Public Can Mitigate Spread of COVID-19

THURSDAY, June 11, 2020 (HealthDay News) — Face-mask use by the public, in combination with physical distancing and periods of lockdown, can mitigate the spread of the new coronavirus, according to a study published online June 10 in the Proceedings of the Royal Society A.

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First Large Clinical Trial of COVID-19 Vaccine in U.S. Could Begin in July

THURSDAY, June 11, 2020 (HealthDay News) — A large clinical trial of the first U.S. COVID-19 vaccine could begin next month, according to Moderna Inc., which developed the vaccine with the U.S. National Institutes of Health.

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COVID-19 Behavior Seems Consistent With Seasonal Virus

THURSDAY, June 11, 2020 (HealthDay News) — Eight cities with substantial community outbreaks of COVID-19 are distributed along restricted latitude, temperature, and humidity measurements, consistent with behavior of a seasonal respiratory virus, according to a study published online June 11 in JAMA Network Open.

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Personal Protective Equipment Prevents SARS-CoV-2 Infection

THURSDAY, June 11, 2020 (HealthDay News) — Appropriate personal protective equipment can protect frontline health care professionals who care for patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published online June 10 in The BMJ.

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Risk Factors for Suicide ID’d in Health Care Professionals

THURSDAY, June 11, 2020 (HealthDay News) — Modifiable and nonmodifiable risk factors for suicide have been identified among health care professionals, according to a study published online June 10 in JAMA Surgery.

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Acalabrutinib Promising for Treatment of Severe COVID-19

THURSDAY, June 11, 2020 (HealthDay News) — For patients with severe COVID-19, treatment with acalabrutinib, a selective bruton tyrosine kinase (BTK) inhibitor, appears to improve oxygenation and reduce measures of inflammation, according to a study published in the June 5 issue of Science Immunology.

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Obesity Linked to Greater Severity of Pediatric COVID-19